Medication info

Doberon Tablet 250 Milligrams (Dobesilic Acid Calcium Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Dobesilate Calcium Hydrate›250mg / 1 tablet
Manufacturer / importer
Guju Pharmaceutical Co., Ltd.
Appearance
White oval tablet
Packaging
30 tablets/bottle, 90 tablets/bottle
Approval status
Active

MFDS item code 202107587 · Approved 2021.11.23

Summary

Main use
Treatment of capillary disorders (such as diabetic retinopathy), venous disorders (such as edema), and hemorrhoids
Who takes it
Adults
Adult dose
Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular lesions and retinopathy: 500~1000mg daily 2. Venous disease: Administer 750mg daily for 1~3 weeks, then 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted according to age and symptoms.

Ingredients

Manufacturer
Guju Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of capillary disorders (such as diabetic retinopathy), venous disorders (such as edema), and hemorrhoids

  • Heightened capillary rupture
  • permeability disorders
  • vascular damage
  • diabetic capillary disorders
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral venous edema
  • hemorrhoids
View approved original text

This medication is used to treat various vascular problems related to capillary damage. It is particularly effective for vascular damage associated with heightened capillary rupture and permeability disorders. It also helps improve capillary disorders due to diabetes and diabetic retinopathy. It is used for the treatment of venous insufficiency and post-thrombotic syndrome, and is useful for alleviating peripheral venous edema and hemorrhoidal symptoms. Overall, it enhances vascular health and improves the symptoms of these conditions.

How to take

Adult dose

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular lesions and retinopathy: 500~1000mg daily 2. Venous disease: Administer 750mg daily for 1~3 weeks, then 500mg daily. Take after meals with plenty of fluids. The dose may be adjusted according to age and symptoms.

Precautions

This medication should not be used in patients with allergic reactions to this medication or its components. Additionally, this medication contains lactose, so it should not be administered to patients with genetic disorders that affect lactose digestion. For patients with poor kidney function, the safety and efficacy of this medication have not been adequately studied, so caution should be used, and the dosage may need to be reduced, especially for patients with severe kidney disease requiring dialysis. For patients with impaired liver function, caution is also advised due to a lack of research on the safety of this medication, and treatment should be re-evaluated if liver enzyme levels rise significantly. This medication contains sodium metabisulfite, which may cause allergic reactions or asthma attacks in some individuals, so asthmatics should be especially cautious. While taking this medication, symptoms such as headache, abdominal pain, nausea, diarrhea, vomiting, arthralgia, and myalgia may occur, and if these symptoms are severe, advice from a physician should be sought. Rarely, serious side effects such as a decrease in blood cell count may occur; therefore, if high fever or signs of infection develop, prompt medical attention is necessary. If hypersensitivity reactions occur, the medication should be discontinued immediately and healthcare personnel notified. The effects on driving or operating machinery are unknown, so caution is advised. It is recommended to avoid using this medication during pregnancy, and breastfeeding should also be refrained from; if necessary, treatment or breastfeeding should be discontinued. The safety and efficacy of this medication have not been sufficiently established for children. No special precautions have been reported for elderly patients over 65 years of age. This medication may affect some blood test results, so testing is advised before taking this medication. No specific symptoms have been reported for overdose, but general emergency treatment should be sought.

Side effects

  • Agranulocytosis
  • neutropenia
  • leukopenia
  • skin rash
  • allergic dermatitis
  • itching
  • urticaria
  • facial swelling
  • anaphylactic reaction
  • headache
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  • abdominal pain
  • nausea
  • diarrhea
  • vomiting
  • increased alanine aminotransferase
  • arthralgia
  • myalgia
  • fever
  • chills
  • lethargy
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

White oval tablet

Package unit

30 tablets/bottle, 90 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.