Empamax M Tablet 12.5/500 mg (Empagliflozin, Metformin)

Adult dose

The recommended dosage of this medication is 1 tablet once daily, administered twice a day. The dosage should be determined considering each patient's treatment regimen, efficacy, and tolerability, without exceeding the maximum daily recommended doses of empagliflozin 25 mg and metformin 2000 mg. For patients who struggle with glycemic control using metformin alone or in combination with other medications such as insulin, the recommended dosage is empagliflozin 5 mg twice daily (total daily amount of 10 mg) along with the previously prescribed dose of metformin.

This medication can cause rare side effects such as severe lactic acidosis, so if symptoms of lactic acidosis appear, immediate consultation with a physician is necessary. Be cautious as hypoglycemia may occur when taken with other diabetes medications. This medication should not be taken by patients with moderate or severe renal impairment. Patients with acute conditions such as acute renal failure, severe infections, or cardiovascular diseases should not be administered this drug. It is safest for pregnant or breastfeeding women to avoid this medication. If surgery is planned or examinations involving iodinated contrast agents are to be conducted, this medication should be discontinued for a certain period. Elderly patients or those with reduced renal function should undergo regular kidney function tests and dosage adjustments may be necessary as required. This medication can increase the risk of urinary tract infections and genital infections, so if related symptoms occur, you should immediately inform a healthcare provider. Alcohol consumption can increase the risk of side effects with this medication, so it's advisable to avoid it while taking this drug. As hypoglycemic symptoms may appear, blood glucose levels should be closely monitored, especially when used in combination with insulin or sulfonylureas. If there are symptoms of fluid loss or dehydration, this medication may be temporarily discontinued; thus, fluid status should be periodically monitored. There is a risk of vitamin B12 deficiency, so it is recommended to regularly check B12 levels during prolonged use. If any unusual symptoms such as fever, genital pain, swelling, rashes occur while taking this medication, immediate consultation with a healthcare provider is advised.

Serious side effects

Hives, angioedema, perineal necrosis, ketoacidosis, lactic acidosis, pyelonephritis, urosepsis, acute kidney injury, acute renal failure, hepatitis, myocardial infarction, cerebral infarction, angina, acute cholecystitis, autoimmune hepatitis, cholelithiasis, concussion, intracerebral hemorrhage, heart failure, hypoglycemia (including severe hypoglycemia), significant edema, serious neurological symptoms (such as headache, confusion, seizures), respiratory distress, pneumonia, sepsis, shock, acute myocardial infarction

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• constipation

This medication must be stored in a tightly closed container to prevent exposure to air or moisture and should be kept at room temperature between 1 to 30 degrees Celsius. Therefore, avoid direct sunlight and do not store it in excessively hot or cold places.

Appearance

Light brownish-purplish, oval, biconvex film-coated tablet

Package unit

60 tablets/box [10 tablets/PTP x 6], 30 tablets/bottle