Empamax M Tablet 12.5/1000 mg (Empagliflozin, Metformin)

Adult dose

The recommended dose of this medication is 1 tablet, twice a day. The maximum recommended daily dose for each ingredient should not exceed empagliflozin 25 mg and metformin 2000 mg. For patients who do not achieve sufficient blood sugar control with monotherapy with metformin or other medications such as insulin, the recommended dosage is 5 mg of empagliflozin twice a day (a total of 10 mg per day) alongside its existing metformin dosage.

This medication may cause a serious side effect called severe lactic acidosis; therefore, patients with poor kidney function or heart disease should use it with caution. Additionally, there is a risk of hypoglycemia when taken with other diabetes medications such as insulin or sulfonylureas, so dose adjustments may be necessary. Patients with moderate or lower kidney function or those in states that may cause acute kidney injury should not use this medication. Patients with serious conditions such as acute infection, dehydration, heart failure, or myocardial infarction, or those scheduled for surgery should temporarily discontinue this medication and may resume it only after their condition stabilizes. Women who are pregnant, may become pregnant, or are nursing should not take this medication. This medication may increase the risk of urinary and genital infections; therefore, patients should consult a physician immediately if symptoms of infection occur. Since vitamin B12 deficiency may occur, it is advisable to regularly check blood vitamin B12 levels when taken for an extended period. Elderly patients or those at risk of fluid loss should carefully manage their fluid status and take the medication according to the physician's instructions, as dehydration and hypotension may occur. This medication may interact with various drugs that affect blood sugar control; thus, patients should inform their physician or pharmacist if they are taking other medications. If symptoms of severe metabolic anomalies such as lactic acidosis or ketoacidosis occur, stop taking the medication immediately and seek medical assistance. In cases of overdose, professional treatment such as blood dialysis may be required; therefore, patients should go to the hospital immediately in an emergency situation.

Serious side effects

Hives, severe swelling (angioedema), lactic acidosis, ketoacidosis, urosepsis, pyelonephritis, perineal necrosis, worsening of kidney disease, acute kidney injury, acute renal failure, liver abnormalities (hepatitis, acute cholecystitis, autoimmune hepatitis), myocardial infarction, cerebral infarction, headache (severe headache, thunderclap headache), altered consciousness, vision disturbances, paralysis, seizures, severe swelling, abnormal urination, increased blood pressure, asthma attack, difficulty breathing,

Mild side effects

• Hypoglycemia
• urinary tract infection
• genital infection
• increased urination
• nausea
• vomiting
• diarrhea
• abdominal pain
• decreased appetite
• constipation

This medication should be stored in a tightly closed container to prevent contact with air or moisture, and the storage temperature should be maintained between 1 and 30 degrees at room temperature. By storing it this way, the effectiveness of the medication can be safely maintained.

Appearance

Biconvex oval film-coated tablets with a dark brownish-purple color

Package unit

60 tablets/box [10 tablets/PVC x 6], 30 tablets/bottle