Poshuvet Duo Sustained Release Tablet 10/1000 Milligrams

Adult dose

This medication is generally administered once daily with dinner. The maximum dosage is dapagliflozin 10 mg/metformin sustained release 2000 mg once daily, given as 2 tablets of 5 mg/1000 mg. For those with no prior experience of diabetes medication therapy, the initial regimen is one tablet of either 5 mg/500 mg or 10 mg/500 mg once daily, to reduce gastrointestinal side effects of metformin, this should be initiated gradually.

This medication is a combination therapy used for the treatment of type 2 diabetes and helps in controlling blood sugar levels. It should not be administered to patients with impaired kidney function or those with acute illness. During treatment, a rare complication called lactic acidosis may occur, and if symptoms such as difficulty breathing, abdominal pain, or weakness arise, healthcare professionals should be notified immediately. This medication may cause hypoglycemia, so caution should be exercised when used alongside insulin or sulfonylurea medications. Elderly patients with reduced kidney function or in a state of dehydration should evaluate their fluid status and kidney function before starting this medication, and their condition should be regularly monitored after administration. This medication may increase the risk of genital and urinary tract infections, so prompt treatment is necessary if any infection symptoms appear. Women who are pregnant or may become pregnant, as well as nursing mothers, should not use this medication. Alcohol consumption should be avoided during treatment, as excessive drinking may increase the risk of lactic acidosis. Before undergoing surgery or radiographic studies using contrast agents, this medication should be discontinued for a period of time, and it should be resumed only after confirming normal kidney function. Vitamin B12 levels may decrease; therefore, regular blood tests are advisable during long-term use. In the event of overdose, immediate treatment at a medical facility is required, and this medication can be removed through dialysis. Store this medication out of reach of children and keep it in its original container for safety. Caution is required when driving or operating machinery, as dizziness may occur.

Serious side effects

• Severe lactic acidosis
• severe hypoglycemia
• lactic acidosis
• acute renal failure
• cardiovascular collapse
• acute myocardial infarction
• sepsis
• severe liver abnormalities
• liver dysfunction
• sudden and severe headache

Mild side effects

• Vulvovaginitis
• balanitis
• related genital infections
• urinary tract infections
• fungal infections
• hypoglycemia
• dry mouth
• dizziness
• constipation
• back pain

Store this medication in a tightly closed container to prevent air or moisture. It is preferable to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

Yellow, double convex, film-coated tablet in the shape of a round pill.

Package unit

30 tablets per bottle