Posimet Extended Release Tablet 10/1000 mg

Adult dose

This medication is generally administered once daily with the evening meal. The maximum dose is 10 mg of dapagliflozin / 2000 mg of extended-release metformin once daily, and it is administered as 2 tablets of 5 mg/1000 mg. When used as initial therapy in patients with no previous experience with diabetes medication, the recommended starting dose is 1 tablet of either 5 mg/500 mg or 10 mg/500 mg once daily. Gastrointestinal side effects of metformin

This medication can very rarely cause severe lactic acidosis, and caution is needed especially in patients with poor kidney function or those with serious infections, dehydration, etc. When used in conjunction with other diabetes medications, there may be an increased risk of hypoglycemia, so blood sugar levels should be closely monitored. Patients with allergies to this medication's main ingredients or additives, severe kidney impairment, acute myocardial infarction, or heart failure should not use this medication. Before and after tests using iodinated contrast agents, this medication should be temporarily discontinued and confirmed that kidney function is normal before resuming use. In patients with low fluid volume or decreased kidney function, their condition should be well evaluated before administration, and blood pressure and kidney function should be continuously monitored during administration. This medication can affect blood sugar control, so when used with insulin or sulfonylureas, dose adjustments may be necessary to prevent hypoglycemia. During treatment, symptoms such as genital infections, urinary tract infections, hypoglycemia, and dehydration may occur, so if any unusual symptoms arise, immediate consultation with healthcare professionals is advised. Women who are pregnant or may become pregnant, or are breastfeeding, should not use this medication. Elderly patients or those with reduced kidney function should have their doses carefully adjusted, and regular kidney function tests are necessary. In case of overdose, immediate visit to a medical institution for appropriate treatment is required, and if necessary, dialysis may be performed to eliminate the drug. Moreover, excessive alcohol consumption should be avoided while taking this medication, and care should be taken when driving or operating machinery as dizziness may occur.

Serious side effects

Lactic acidosis, severe hypoglycemia, severe infections, acute myocardial infarction, acute renal failure, acute kidney injury, ketoacidosis, urosepsis, pyelonephritis, perineal necrosis, severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness), severe dermatological reactions (severe rash, blisters, skin peeling, pain in mouth/eyes with high fever), respiratory problems (shortness of breath or difficulty breathing,

Mild side effects

• Vulvovaginitis
• balanitis and related genital infections
• urinary tract infections
• fungal infections
• hypoglycemia
• dry mouth
• dizziness
• constipation
• back pain
• dysuria

This medication should be stored in a tightly sealed container to prevent air and moisture ingress, and it is important to maintain a storage temperature between 1 to 30 degrees at room temperature. Proper storage will help maintain the medication's effectiveness longer.

Appearance

Yellow, film-coated, bilaterally convex egg-shaped tablet

Package unit

30 tablets/bottle