Y2Met 500 mg Tablet (Metformin Hydrochloride)

Adult dosage

Dosage should be determined based on the individual's response to the medication and tolerance, and must not exceed the recommended maximum daily dose. This medication should start at a low dose to reduce gastrointestinal adverse reactions and determine the minimum effective dose required for appropriate blood sugar control, typically administered at 500 mg with meals 2-3 times a day. Dosage increases should be gradual, raising by 500 mg weekly until reaching 2000 mg. If dosing exceeds 2000 mg, it should be divided into 3 doses with meals and can reach a maximum of 2550 mg per day. When starting treatment and adjusting dosages, fasting blood glucose should be measured to assess the response to this medication and confirm the minimum effective dose. The glycated hemoglobin concentration should be measured approximately every 3 months. The treatment goal is to reduce fasting blood sugar and glycated hemoglobin to normal or near-normal levels when administered alone or in conjunction with sulfonylureas or insulin at the minimum effective dose. Generally, in patients whose blood sugar was previously controlled solely with diet, this medication can provide sufficient effect even if used for a short time when blood sugar control temporarily fails.

Children's dosage

Can be used in children aged 10 years and older or adolescents in their growth period, with a typical starting dose of 500 mg once daily. Administer during or after meals, and measure blood sugar levels after one week.

This medication is used to lower blood sugar and should not be used in patients with impaired kidney function. Patients with severe infections, dehydration, or conditions affecting kidney function, such as acute myocardial infarction, may also be at risk when taking this medication. Do not use this medication if heart failure is acute or unstable, and temporarily discontinue before and after tests using certain contrast agents. It is not administered to individuals with previous allergic reactions to this medication, those with Type 1 diabetes, or patients with severe metabolic acidosis. Patients scheduled for surgery should discontinue use of this medication 48 hours before the procedure and resume only after kidney function is confirmed to be normal. Patients with very poor nutritional status or impaired liver function should also use this medication with caution. While taking this medication, serious side effects such as hypoglycemia or lactic acidosis may occur. If abnormal symptoms arise, notify medical personnel immediately. Particularly, lactic acidosis, while rare, can be fatal, so be cautious of symptoms such as fatigue, muscle pain, and shortness of breath. Gastrointestinal symptoms may occur frequently but usually improve over time; dosage adjustments may be necessary if symptoms are severe. This medication is primarily excreted through the kidneys, so regular monitoring of kidney function is necessary, and if any abnormalities arise, discontinue use. Alcohol consumption may increase the risk of side effects of this medication, so excessive drinking should be avoided. Blood sugar control status should be monitored regularly, and dosage adjustments or changes in treatment methods may be necessary based on needs. During pregnancy, the effects on the fetus should be considered, and use should be exercised with caution; discontinue use if problems with fetal growth are detected. During breastfeeding, since this medication may be excreted into breast milk, careful consideration should be given regarding whether to continue breastfeeding and use of the medication. In the elderly, decreased kidney function is common, so treatment should start at a low dose, regularly checking kidney function during the course. Drug interactions may occur when combined with other medications, so any other medications being taken should be disclosed to medical personnel. In the case of overdose, this medication can be removed by dialysis, so if an overdose is suspected, seek medical attention immediately. This medication does not cause weight gain and may actually help with weight maintenance or loss.

Serious side effects

Lactic acidosis (fatigue, muscle pain, shortness of breath, weakness, abdominal pain, hypothermia, hypotension, resistant bradyarrhythmia), severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor), severe skin adverse reactions (severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa), respiratory issues (shortness of breath or difficulty breathing, asthma attacks, coughing with fever accompanied by respiratory anomalies.

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, indigestion, constipation, abdominal pain), unpleasant or metallic taste, rash, anemia, leukopenia, thrombocytopenia, vitamin B12 deficiency, liver function abnormalities, severe delayed hypoglycemia.

Store this medication in a sealed container to prevent air ingress, and keep it at a safe temperature between 1 degrees and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness and prevents deterioration.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 500 tablets/bottle