Yturosuvastatin 5 mg (Rosuvastatin Calcium) Tablet

Adult dosage

Administer 5 mg once daily as the initial dose, irrespective of meals. If a greater reduction in LDL cholesterol is required, it can be adjusted to 10 mg as a maintenance dose once daily. The dose should be appropriately adjusted based on LDL cholesterol levels, therapeutic goals, and patient response, with a minimum interval of 4 weeks. The maximum daily dose is 20 mg.

Children's dosage

Pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years) should be administered a dose between 5 mg and 20 mg once daily. The dosage should be individually adjusted according to the therapeutic goals for each patient.

This medication should not be used in certain patients. For example, individuals allergic to the components of this medication, those with severely impaired liver function, muscle disorders, those taking certain immunosuppressants, individuals with severe renal impairment, pregnant or breastfeeding women, and individuals with specific genetic diseases should not take this medication. Moreover, before taking this medication, it is essential to inform if there is a history of liver or kidney disease, thyroid dysfunction, or muscle disorders, as these patients should use this medication cautiously. This medication can cause muscle pain, weakness, and, rarely, severe muscle damage; therefore, if any unusual muscle symptoms occur, the physician should be informed immediately. It is important to receive regular liver function tests and muscle enzyme tests, especially when taking high doses. Caution is also necessary for those who consume alcohol heavily or have a history of liver disease. This medication can interact with other drugs, so it is crucial to inform healthcare providers of any other medications being taken. Particularly, muscle damage risk may increase when taken with certain antiviral agents, immunosuppressants, and fibrate medications. Women who are pregnant or may become pregnant must not use this medication and should implement appropriate contraception methods. Breastfeeding women should also avoid taking this medication. In the case of overdose, there is no specific antidote, so it is imperative to visit a medical facility immediately for treatment based on symptoms and to monitor liver function and muscle enzyme levels. This medication is not known to significantly affect driving or machine operation abilities; however, caution is warranted as dizziness may occur after intake. Lastly, if severe skin rashes or allergic reactions occur during treatment, it is essential to discontinue use immediately and consult a healthcare professional.

Serious side effects

Allergic reactions including hives and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), rhabdomyolysis, immune-mediated necrotizing myopathy, severe muscle weakness, ocular myasthenia gravis, respiratory distress, hepatitis, jaundice, acute renal failure, thrombocytopenia, fatal and non-fatal liver failure, severe skin reactions, neurological effects (including polyneuropathy, severe muscle weakness)

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• hematuria

This medication must be stored in a tightly sealed container to prevent exposure to air and moisture. It is essential to maintain storage temperatures between 1 degree and 30 degrees Celsius at room temperature. This helps maintain the effectiveness of the medication and ensures safe use.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle, 30 tablets/box [15 tablets/PTP (Alu-Alu) x 2]