Medication info
Dobetella Tablet 500 mg (Dobesil Calcium Hydrate)

Dobetella Tablet 500 mg (Dobesil Calcium Hydrate)

Prescription medicationTabletOral
Ingredient · strength
Dobesilate Calcium Hydrate›500mg / 1 tablet
Manufacturer / importer
Anguk Pharmaceutical Co., Ltd.
Appearance
White rectangular tablet
Packaging
30 tablets/bottle, 90 tablets/bottle
Approval status
Active

MFDS item code 202106756 · Approved 2021.10.06 · Insurance code 650206020

Summary

Main use
Improvement of capillary disorders (e.g., diabetic retinopathy), venous disorders (e.g., edema), and hemorrhoids
Who takes it
Adults
Adult dose
Adults: Administer the following doses orally as calcium dobesilate hydrate. 1. Vascular lesions and retinopathy: 500~1000mg per day 2. Venous disease: Administer 750mg per day for 1~3 weeks, then administer 500mg per day. Take after meals with plenty of fluids. The dose may be adjusted as appropriate according to age and symptoms.

Ingredients

Manufacturer
Anguk Pharmaceutical Co., Ltd.

Efficacy & effects

Improvement of capillary disorders (e.g., diabetic retinopathy), venous disorders (e.g., edema), and hemorrhoids

  • Increased capillary rupture
  • permeability disorders
  • vascular damage
  • diabetic microvascular disorder
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral congestive edema
  • hemorrhoids
View approved original text

This medication is used for vascular damage accompanied by increased capillary rupture and permeability disorders, diabetic microvascular disorders, and diabetic retinopathy. It is also effective for vascular-related issues such as venous insufficiency, post-thrombotic syndrome, peripheral congestive edema, and hemorrhoids. It helps restore vascular health and relieve symptoms by improving these conditions.

How to take

Adult dose

Adults: Administer the following doses orally as calcium dobesilate hydrate. 1. Vascular lesions and retinopathy: 500~1000mg per day 2. Venous disease: Administer 750mg per day for 1~3 weeks, then administer 500mg per day. Take after meals with plenty of fluids. The dose may be adjusted as appropriate according to age and symptoms.

Precautions

This medication contains Dobesil Calcium Hydrate as its main ingredient and should not be used in certain patients. Firstly, patients who are allergic to this medication or its components, pregnant or nursing women, and patients who have genetic issues in breaking down or absorbing lactose should not take this medication. Additionally, it should be used with caution in patients with impaired kidney function. Since this medication is eliminated through the kidneys, dosage adjustments may be required if drug concentrations increase due to weak kidney function. Patients with decreased liver function should also use it carefully, and if abnormal reactions such as elevated liver enzymes occur, the treatment benefits should be reassessed. This medication contains sulfite, which can cause serious allergic reactions such as asthma attacks in patients allergic to sulfites or asthmatic patients, so caution is required. Common side effects may include headaches, abdominal pain, nausea, diarrhea, vomiting, joint pain, muscle pain, and elevated liver enzyme levels. Rarely, serious blood abnormalities or severe allergic reactions such as anaphylaxis may occur. If symptoms of infection such as high fever, sore throat, or oral infections appear, inform a doctor immediately, and blood tests should be conducted to check the condition, and the medication should be discontinued if necessary. If an allergic reaction is suspected, discontinue the medication immediately and consult healthcare professionals. There are no known interactions of this medication with other drugs, but it may affect creatinine level measurements during blood tests, so inform healthcare providers about taking this medication before tests. Also, necessary tests such as blood tests should be conducted before taking this medication for safe usage.

Side effects

  • Agranulocytosis
  • neutropenia
  • leukopenia
  • skin rash
  • allergic dermatitis
  • itching
  • urticaria
  • facial swelling
  • anaphylactic reaction
  • headache
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  • abdominal pain
  • nausea
  • diarrhea
  • vomiting
  • increased alanine aminotransferase
  • arthralgia
  • myalgia
  • fever
  • chills
  • lethargy
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a special container that blocks light. Additionally, it is best to store it at room temperature between 1 and 30 degrees Celsius. Storing it this way can maintain the effectiveness and safety of the medication.

Appearance and packaging

Appearance

White rectangular tablet

Package unit

30 tablets/bottle, 90 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.