Medication info
Dobra Tablet 500 mg (Dovesil Calcium Hydrate)

Dobra Tablet 500 mg (Dovesil Calcium Hydrate)

Prescription medicationTablet
Ingredient · strength
Dobesilate Calcium Hydrate›500mg / 1 tablet
Manufacturer / importer
Intro BioPharma Co., Ltd.
Appearance
White rectangular tablet
Packaging
Bottle packaging - 30 tablets/bottle, Bottle packaging - 60 tablets/bottle, Bottle packaging - 90 tablets/bottle
Approval status
Active

MFDS item code 202106451 · Approved 2021.09.09 · Insurance code 052402130

Summary

Main use
Treatment of capillary disorders and venous disorders (e.g., hemorrhoids and peripheral congestive edema)
Who uses it
Adults
Adult dosage
Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disease: Administer 750mg daily for 1~3 weeks, then administer 500mg daily. Take after meals with plenty of fluids. Adjust the dose as appropriate according to age and symptoms.

Ingredients

Manufacturer
Intro BioPharma Co., Ltd.

Efficacy & effects

Treatment of capillary disorders and venous disorders (e.g., hemorrhoids and peripheral congestive edema)

  • Increased capillary rupture
  • permeability disorder
  • vascular damage
  • diabetic microangiopathy
  • diabetic retinopathy
  • venous insufficiency
  • post-thrombotic syndrome
  • peripheral congestive edema
  • hemorrhoids
View approved original text

This drug is used for various vascular and circulatory diseases accompanied by increased capillary rupture and permeability disorders, such as vascular damage, diabetic microangiopathy, diabetic retinopathy, venous insufficiency, post-thrombotic syndrome, peripheral congestive edema, and hemorrhoids.

Dosage and Administration

Adult dosage

Adults: Administer the following doses of calcium dobesilate hydrate orally. 1. Vascular damage and retinopathy: 500~1000mg daily 2. Venous disease: Administer 750mg daily for 1~3 weeks, then administer 500mg daily. Take after meals with plenty of fluids. Adjust the dose as appropriate according to age and symptoms.

Precautions

This drug is made from the ingredient Dovesil Calcium Hydrate. This drug should not be used by individuals who have allergic reactions to Dovesil Calcium Hydrate or other ingredients of this drug, as well as women who are pregnant or breastfeeding. Additionally, since it contains lactose, individuals with problems in lactose digestion or genetic diseases such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption should not take this drug. In patients with impaired kidney function, the safety and efficacy of this drug have not been sufficiently studied, and caution is required. In particular, in severe cases of renal failure requiring dialysis, the dosage of the drug may need to be reduced. Patients with impaired liver function should also exercise caution when using this drug, and if liver enzyme levels rise, the benefits and risks of treatment should be reevaluated. This drug contains sulfites, so individuals sensitive to sulfites, especially those with asthma, should be careful as allergic reactions or asthma attacks may occur. Various adverse reactions may appear when taking this drug, with common symptoms including headache, abdominal pain, nausea, diarrhea, vomiting, elevated liver enzymes, and joint and muscle pain. Rarely, severe blood disorders such as agranulocytosis or severe allergic reactions like anaphylaxis may occur, so if these symptoms appear, you should inform your doctor immediately. If gastrointestinal disturbances are severe, the dosage may be reduced or temporarily discontinued. If skin rash, fever, joint pain, or changes in blood counts occur, these may indicate hypersensitivity, so treatment must be discontinued and consultation with a doctor is necessary. While taking this drug, if symptoms of infection or fever develop, you should inform your healthcare provider immediately, and blood tests may be required to check your condition. This drug may cause severe allergic reactions, so if symptoms appear, you must stop taking it immediately. There are no known special interactions with other drugs, but since this drug may affect blood test results, you should inform your healthcare provider before undergoing tests.

Side effects

  • Agranulocytosis
  • neutropenia
  • leukopenia
  • skin rash
  • allergic dermatitis
  • itching
  • hives
  • facial swelling
  • anaphylactic reaction
  • headache
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  • abdominal pain
  • nausea
  • diarrhea
  • vomiting
  • increased alanine aminotransferase
  • arthralgia
  • myalgia
  • fever
  • chills
  • lethargy
  • fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a tightly closed container that can block light and kept at room temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

White rectangular tablet

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 60 tablets/bottle, Bottle packaging - 90 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.