Innoen Empagliflozin 10 mg

Adult dose

The recommended dose of this medication is 10 mg once daily for monotherapy and for additional combination therapy with other blood glucose-lowering agents such as insulin. If the patient tolerates 10 mg well but requires additional blood sugar control, the dose may be increased to 25 mg once daily. This medication can be taken regardless of meals. Swallow the tablet whole. If a dose is missed, take it as soon as remembered.

This medication should not be given to certain patients. For example, individuals with allergies to the active ingredient or components of this medication should not take it. Additionally, it is contraindicated in patients with type 1 diabetes or diabetic ketoacidosis. Patients with severely impaired kidney function, such as those with a glomerular filtration rate below 30 mL/min/1.73m2 or those with end-stage renal disease or on dialysis should not take this medication. This medication contains lactose; patients with genetic issues such as galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not take it. Careful administration is required for patients with slightly impaired kidney function, and treatment initiation should be avoided in those with a glomerular filtration rate below 60 mL/min/1.73m2, and dosage adjustments or discontinuation may be necessary. Caution is needed for patients with heart failure in NYHA class I-II, and it is not recommended for those in class III-IV. When used with insulin or sulfonylureas, there is a risk of hypoglycemia, so dosage adjustments may be necessary. Common side effects reported include hypoglycemia, genital infections (vulvovaginal candidiasis, vulvitis, glans inflammation, etc.), urinary tract infections, increased urination, decreased body fluid volume, skin rash, and urticaria. Particularly, serious metabolic acidosis such as ketoacidosis may occur, and if symptoms like nausea, vomiting, abdominal pain, or difficulty breathing arise, immediate consultation with medical personnel is necessary. Care is required for the elderly or patients at risk of fluid loss due to potential hypotension or dehydration. This medication may have a slight impact on driving or operating machinery; especially those at risk of hypoglycemia should be cautious. Use is not recommended for pregnant women; if pregnancy is confirmed, treatment should be discontinued. Breastfeeding should be stopped if this medication is taken while nursing. The safety and efficacy in pediatric patients under 18 years have not been established. No specific toxic symptoms have been reported in the case of overdose, but appropriate treatment according to clinical condition is necessary. This medication should be kept out of reach of children and should not be transferred to other containers. Finally, this medication may interact with other drugs, so it is important to consult with healthcare professionals, especially when used in combination with diuretics, insulin, or sulfonylureas.

Serious side effects

• Urticaria
• angioedema
• perineal necrosis
• ketoacidosis
• urosepsis
• pyelonephritis

Mild side effects

Vulvovaginal candidiasis, vulvitis, glans inflammation and other genital infections, hypoglycemia (when used with sulfonylureas or insulin), rash, itching, increased urination, urination difficulty, interstitial nephritis, thirst, increased serum lipids, increased serum creatinine, decreased glomerular filtration rate, increased hematocrit, decreased fluid volume, hypotension, dehydration, reduced blood volume, orthostatic hypotension, syncope

This medication should be stored in a closed container to protect it from air or moisture. The storage temperature should be maintained between 1 and 30 degrees Celsius.

Appearance

Pale yellow round film-coated tablets

Package unit

30 tablets - 30 tablets/PTP [(10 tablets/PTP×3)], 10 tablets - 10 tablets/PTP [(10 tablets/PTP×1)]