Ketobazet Tablets 10/20 Milligrams

Adult dosage

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, doses from 10/10mg to 10/80mg per day are administered. The initial dose recommended is either 10/10mg or 10/20mg per day. If a greater reduction in LDL cholesterol (more than 55%) is required, an initial dose of 10/40mg per day is recommended. After initiation of therapy, lipid levels in the blood should be assessed at intervals of more than 2 weeks.

This medication can cause a rare side effect affecting the muscles known as rhabdomyolysis, so if symptoms of severe muscle pain or weakness occur, the physician should be notified immediately. In particular, patients at risk of compromised kidney function due to severe infections, hypotension, major surgery, or trauma should temporarily discontinue or suspend this medication. Patients allergic to any components contained in this medication, those with liver disease or muscle conditions, and pregnant or nursing women should not take this medication. Additionally, patients with certain antiviral medications or lactose intolerance should also avoid this medication. Caution should be exercised when using this medication in patients at high risk of muscle problems such as those with alcohol dependence, liver dysfunction, impaired kidney function, hypothyroidism, or the elderly, and regular testing is required. There is an increased risk of muscle abnormalities when taken together with fibrate medications, so caution is needed. Liver function can be affected by this medication, hence liver function tests should be performed before and during treatment, and immediate consultation with a physician should occur if any signs of liver damage appear. Pregnant women should not take this medication as it may be harmful to the fetus, and women of childbearing age should use appropriate contraception during treatment. The safety and efficacy of this medication in children have not been established, thus it is not recommended. In cases of overdose, no specific antidote exists, therefore treatment and supportive care according to symptoms are necessary, and liver function and muscle enzyme levels should be monitored regularly. Dizziness may occur while taking this medication, so caution is advised during driving or operating machinery. Finally, this medication can interact with several other medications, so it is essential to consult with a doctor or pharmacist if other medications are being taken.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or shortness of breath, asthma attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, vision abnormalities, paralysis, urination.

Mild side effects

• Muscle pain
• abdominal pain
• nausea
• diarrhea
• dizziness
• headache
• fatigue
• cough
• joint pain
• muscle weakness

This medication may be sensitive to air or moisture, so it must be stored in a tightly closed container. It is important to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature. This ensures that the medication's effectiveness is well preserved and can be used safely.

Appearance

A film-coated tablet that is capsule-shaped with a white or pale yellow color and is biconvex on both sides.

Package unit

30 tablets/box [10 tablets/Alu-Alu x 3]