Medication info

Bastia 23 mg (Donepezil Hydrochloride)

Prescription medicationTablet경구
Ingredient · strength
Donepezil Hydrochloride Hydrate›24mg / 1 tablet
Manufacturer / importer
(주)한국파마
Appearance
Red, biconvex, round film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202103492 · Approved 2021.04.29

Summary

Main use
Treatment of moderate to severe Alzheimer's dementia symptoms
Who takes it
Adults
Adult dose
This medication is taken once daily just before bedtime and can be taken without regard to food. The initial recommended dosage of Donepezil Hydrochloride is 5 mg once daily. This medication reaches a steady state after 15 days of administration and should be taken at 5 mg for 4-6 weeks. After evaluating the clinical response, the dosage can be increased to 10 mg. If increasing to 10 mg daily, observe for gastrointestinal adverse reactions.

Ingredients

Manufacturer
(주)한국파마

Efficacy & effects

Treatment of moderate to severe Alzheimer's dementia symptoms

  • Alzheimer's dementia symptoms
View approved original text

This medication is used to treat moderate to severe Alzheimer's dementia symptoms. It is prescribed to help alleviate cognitive decline and memory loss in patients, and to assist in maintaining daily living abilities. Additionally, it contributes to improvements in behavior and social function, thereby helping to enhance the quality of life for the patient.

How to take

Adult dose

This medication is taken once daily just before bedtime and can be taken without regard to food. The initial recommended dosage of Donepezil Hydrochloride is 5 mg once daily. This medication reaches a steady state after 15 days of administration and should be taken at 5 mg for 4-6 weeks. After evaluating the clinical response, the dosage can be increased to 10 mg. If increasing to 10 mg daily, observe for gastrointestinal adverse reactions.

Precautions

This medication is a drug containing Donepezil Hydrochloride, used for the treatment of Alzheimer's dementia symptoms. This medication should not be administered to certain patients. For example, patients with allergies to this medication or its components, pregnant women or women who may become pregnant, and patients with genetic issues such as lactose intolerance should not take this medication. Patients with heart diseases or who are taking non-steroidal anti-inflammatory drugs, patients with a history of asthma or obstructive pulmonary diseases, patients with extrapyramidal disorders such as Parkinson's Disease, and patients allergic to the yellow dye No. 4 contained in this medication should use it cautiously. This medication may cause a slow or irregular heartbeat and can lead to various severe side effects such as peptic ulcers, gastrointestinal bleeding, liver dysfunction, cerebrovascular issues, and muscle problems. If these symptoms occur, immediate consultation with a physician is necessary. Furthermore, while taking this medication, side effects like nausea, vomiting, diarrhea, loss of appetite, dizziness, insomnia, headache, and fatigue may occur, most of which are transient and mild. This medication is approved for use only in patients with Alzheimer's dementia and should not be used for other types of dementia or memory disorders. Treatment should be conducted under the supervision of an experienced physician, and discontinuation should be considered if there is no effect. Patients with heart diseases or electrolyte imbalances are at risk of arrhythmias and may require an electrocardiogram. Additionally, patients with gastrointestinal issues should be cautious of symptom exacerbation. This medication may affect driving or operating machinery, so caution is required at the beginning of treatment or when changing dosages. Women who are pregnant or breastfeeding should avoid taking this medication unless absolutely necessary and should consult a specialist. This medication may interact with multiple drugs, so if taking other medications, it is imperative to inform a physician or pharmacist. In cases of overdose, symptoms such as nausea, vomiting, bradycardia, hypotension, and respiratory depression may occur, and immediate emergency treatment is required; atropine may be used as an antidote. Finally, this medication should be kept out of reach of children and should not be transferred to another container for safety.

Side effects and when to seek care immediately

Serious side effects

  • Syncope
  • bradycardia
  • heart block
  • prolonged QT interval
  • myocardial infarction
  • heart failure
  • peptic ulcer
  • perforated duodenal ulcer
  • gastrointestinal bleeding
  • hepatitis
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  • liver dysfunction
  • jaundice
  • cerebral seizure
  • epilepsy
  • convulsions
  • cerebral hemorrhage
  • cerebrovascular disorders
  • motor function disorders
  • ataxia
  • movement disorders
  • dystonia
  • tremor
  • involuntary movements
  • gait disturbance
  • abnormal posture
  • speech disorders
  • neuroleptic malignant syndrome
  • catatonia
  • rigidity
  • dysphagia
  • tachycardia.

Mild side effects

  • Nausea
  • vomiting
  • diarrhea
  • loss of appetite
  • headache
  • fatigue
  • weakness
  • fever
  • dizziness
  • insomnia
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  • drowsiness
  • muscle pain
  • itching
  • rash
  • thrombocytopenia
  • anxiety
  • aggressive behavior
  • tremor
  • gait disturbance
  • involuntary movements
  • decreased concentration
  • mental dullness
  • facial flushing
  • toothache
  • malaise
  • dehydration
  • hyperlipidemia
  • hypertension
  • hypotension
  • palpitations
  • atrial fibrillation
  • ventricular tachycardia
  • prolonged QT interval on ECG
  • constipation
  • abdominal disorders.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a well-closed container that is airtight, at a temperature between 1 degrees to 30 degrees Celsius at room temperature. This storage will help maintain the medication's effectiveness over time.

Appearance and packaging

Appearance

Red, biconvex, round film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.