Medication info
Danacox 30 mg (Etoricoxib)

Danacox 30 mg (Etoricoxib)

Prescription medicationTabletOral
Ingredient · strength
Etoricoxib›30mg / 1 tablet
Manufacturer / importer
Aju Pharmaceuticals Co., Ltd.
Appearance
Blue-green, round, film-coated tablet with a biconvex surface
Packaging
30 tablets/box [10 tablets/PTP x 3]
Approval status
Active

MFDS item code 202103411 · Approved 2021.04.27 · Insurance code 654005740

Summary

Main use
Relief of symptoms and signs of osteoarthritis (degenerative arthritis)
Who takes it
Adults
Adult dose
The potential risks and benefits of this medication and alternative treatments should be considered before treatment is started. As cardiovascular risk increases with higher doses and longer exposure, use this medication for the shortest possible duration. Adverse reactions such as hypertension, congestive heart failure, and edema may occur during treatment. Reassess at least monthly whether treatment should be continued based on symptom relief and the patient's response to treatment. This medication may be taken with or without food. Adults: The recommended dose is 30 mg once daily. Do not exceed 30mg per day. If there is no therapeutic benefit at the recommended dose, discontinue this medication and consider an appropriate alternative treatment. Patients with hepatic impairment: No dosage adjustment is necessary in patients with mild or moderate hepatic impairment (Child-Pugh score 5-9). However, use caution because experience with this medication in patients with moderate hepatic impairment is limited. Do not use this medication in patients with severe hepatic impairment (Child-Pugh score >9), as there is no experience with its use in these patients. Patients with renal impairment: No dosage adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance of 30 mL/min or greater). Do not use this medication in patients with severe renal impairment (creatinine clearance below 30 mL/min). Elderly patients: No dosage adjustment is necessary in elderly patients.

Ingredients

Manufacturer
Aju Pharmaceuticals Co., Ltd.

Efficacy & effects

Relief of symptoms and signs of osteoarthritis (degenerative arthritis)

  • Symptoms of osteoarthritis
  • symptoms of degenerative arthritis
  • signs of osteoarthritis
  • signs of degenerative arthritis
View approved original text

This medication is used to relieve pain and inflammation caused by osteoarthritis, also known as degenerative arthritis. It selectively inhibits the COX-2 enzyme, reducing inflammation and helping to alleviate pain. However, since each patient has different overall health status and risk factors, it is important to assess risks before use. This attention allows for safe therapy and expected treatment effectiveness. Therefore, this medication is used to relieve osteoarthritis symptoms.

How to take

Adult dose

The potential risks and benefits of this medication and alternative treatments should be considered before treatment is started. As cardiovascular risk increases with higher doses and longer exposure, use this medication for the shortest possible duration. Adverse reactions such as hypertension, congestive heart failure, and edema may occur during treatment. Reassess at least monthly whether treatment should be continued based on symptom relief and the patient's response to treatment. This medication may be taken with or without food. Adults: The recommended dose is 30 mg once daily. Do not exceed 30mg per day. If there is no therapeutic benefit at the recommended dose, discontinue this medication and consider an appropriate alternative treatment. Patients with hepatic impairment: No dosage adjustment is necessary in patients with mild or moderate hepatic impairment (Child-Pugh score 5-9). However, use caution because experience with this medication in patients with moderate hepatic impairment is limited. Do not use this medication in patients with severe hepatic impairment (Child-Pugh score >9), as there is no experience with its use in these patients. Patients with renal impairment: No dosage adjustment is necessary in patients with mild or moderate renal impairment (creatinine clearance of 30 mL/min or greater). Do not use this medication in patients with severe renal impairment (creatinine clearance below 30 mL/min). Elderly patients: No dosage adjustment is necessary in elderly patients.

Precautions

This medication may pose a risk of gastrointestinal bleeding in individuals who regularly consume more than three alcoholic beverages daily, so it should be discussed with a doctor or pharmacist. This medication can affect the cardiovascular system, potentially leading to serious cardiovascular issues such as myocardial infarction or stroke, so it should be used for the minimum necessary duration and dosage. Individuals with a risk of ulcers or gastrointestinal bleeding should take caution when using this medication, and any symptoms such as epigastric pain, black stools, or vomiting blood should prompt immediate consultation with healthcare personnel. Individuals with a history of allergic reactions to this medication or hypersensitivity to aspirin or other non-steroidal anti-inflammatory drugs should not take it. Patients with uncontrolled hypertension, heart failure, or severe liver or kidney disease should avoid this medication. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medication, and if pregnancy is confirmed, use should be discontinued immediately. This medication can affect liver and kidney function, so individuals with liver or kidney disease, as well as the elderly, require strict management by a doctor during use. Dizziness or drowsiness may occur during treatment, so caution should be exercised when driving or operating machinery. There may be interactions with other medications, so it is essential to inform your doctor if taking anticoagulants, diuretics, ACE inhibitors, oral contraceptives, or other medications. If taking this medication long-term, regular blood tests and liver and kidney function tests should be conducted, and any abnormal symptoms should be reported to healthcare personnel immediately. In case of overdose, symptoms such as vomiting, drowsiness, lethargy may occur; in severe cases, there may be kidney failure or respiratory depression, necessitating immediate treatment. This medication should be kept out of the reach of children and should not be transferred to other containers for safety.

Side effects

Gastrointestinal bleeding, serious cardiovascular thrombotic reactions, myocardial infarction, stroke, osteomyelitis, gastroenteritis, upper respiratory tract infection, urinary tract infection, anemia, leukopenia, thrombocytopenia, hypersensitivity reactions, angioedema, anaphylaxis, shock, edema, fluid retention, increased appetite, decreased appetite, weight gain, anxiety, depression, diminished mental capacity, hallucinations, confusion, restlessness, dizziness, headache, dysgeusia, insomnia, sensory disturbances, sensory loss, drowsiness, intracranial hemorrhage, blurred vision, conjunctivitis, tinnitus, vertigo, palpitations, arrhythmia, atrial fibrillation, tachycardia, congestive heart failure, nonspecific ECG changes, angina pectoris, hypertension, flushing, cerebrovascular events, transient ischemic attack, hypertensive crisis, vasculitis, deep vein thrombosis, bronchospasm, cough, dyspnea, epistaxis, pulmonary embolism, abdominal pain, constipation, abdominal distension, gastritis, heartburn, acid reflux, diarrhea, dyspepsia, upper abdominal discomfort, nausea, vomiting, esophagitis, oral ulcer, abdominal bloating, changes in bowel movement, dry mouth, gastric-duodenal ulcer, gastrointestinal perforation, peptic ulcer, irritable bowel syndrome, pancreatitis, increased alanine aminotransferase, increased aspartate aminotransferase, hepatitis, liver failure, jaundice, petechiae, facial swelling, pruritus, rash, erythema, urticaria, Stevens-Johnson syndrome, toxic epidermal necrolysis, fixed drug eruption, muscle cramps, musculoskeletal pain, musculoskeletal stiffness, proteinuria, increased serum creatinine, renal failure, renal dysfunction, asthenia, fatigue, flu-like illness, chest pain, increased blood urea nitrogen, increased creatine phosphokinase, hyperkalemia, increased uric acid, decreased serum sodium, facial swelling, chest discomfort, tremors, visual disturbances

Not everyone experiences these, and they can vary from person to person.

Storage

This medication can be sensitive to air and humidity, so it must be stored in a tightly sealed container. The storage temperature should be kept at room temperature between 1 and 30 degrees. Proper storage will help maintain the medication's effectiveness over time.

Appearance and packaging

Appearance

Blue-green, round, film-coated tablet with a biconvex surface

Package unit

30 tablets/box [10 tablets/PTP x 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.