Onept 23mg (Donepezil Hydrochloride Hydrate)

Adult dose

This medication should be taken once daily just before bedtime and can be taken regardless of food. The initial recommended dose of donepezil hydrochloride is 5mg once daily. After administering 5mg for 4 to 6 weeks and assessing clinical response, the dose may be increased to 10mg. When increasing to a daily dose of 10mg, caution should be taken regarding gastrointestinal adverse reactions. After taking 10mg for a minimum of 3 months, 23mg may be taken once daily.

This medication contains donepezil hydrochloride as its active ingredient and is used for the treatment of Alzheimer's type dementia symptoms. This medication should be avoided in certain patients, for example, in those who are allergic to this medication or its components, in pregnant women or women who may become pregnant, in breastfeeding women, and in patients with lactose intolerance or certain genetic metabolic disorders. Patients with heart disease or heart conduction disorders should use this medication with extreme caution. This medication can slow heart rate or cause arrhythmias. Patients with a history of peptic ulcers or those taking non-steroidal anti-inflammatory drugs should be cautious as this medication may increase the risk of gastrointestinal bleeding or worsen ulcers. Patients with a history of asthma or obstructive pulmonary disease should use this medication carefully as it may exacerbate symptoms due to bronchoconstriction and increased mucus secretion. Patients with extrapyramidal disorders such as Parkinson's disease should be cautious as this medication may worsen symptoms. This medication contains a dye called Tartrazine (Yellow No. 4), and caution should also be exercised if allergic to this component. Various adverse reactions may occur with this medication. In severe cases, symptoms such as fainting, bradycardia, heart block, myocardial infarction, gastrointestinal bleeding, liver dysfunction, cerebrovascular accidents, and muscle disorders may arise, so if these symptoms occur, consult a doctor immediately. Generally, nausea, vomiting, diarrhea, loss of appetite, dizziness, insomnia, headache, and fatigue are commonly reported, and these symptoms are usually mild or temporary. This medication may increase the risk of adverse effects when taken with other medications that affect heart conduction, especially antiarrhythmics, certain antidepressants, and antipsychotic medications, so caution is needed when used together. Pregnant or breastfeeding women should avoid using this medication unless absolutely necessary, and should consult a professional before making a careful decision. Safety in children has not been established, and its use is not recommended. This medication may affect liver and kidney function, so it is important to monitor the condition with regular tests. In case of overdose, symptoms such as nausea, vomiting, bradycardia, respiratory depression, and seizures may occur, necessitating immediate emergency care, and atropine can be used as an antidote. This medication should be stored out of the reach of children, and transferring it to another container should be avoided as it may compromise quality.

Serious side effects

Severe allergic reactions (hives, severe swelling), severe skin reactions (severe rash, blisters, skin peeling, pain in the mouth/eyes), respiratory issues (difficulty breathing, asthma attacks), liver abnormalities (jaundice, hepatitis, liver dysfunction), severe neurological symptoms (severe headache, cerebral seizures, convulsions, cerebral hemorrhage, cerebrovascular disorders, confusion, paralysis), severe swelling or urination issues (generalized severe swelling, decreased urination), and heart problems.

Mild side effects

Mild to moderate adverse reactions including nausea, vomiting, diarrhea, loss of appetite, headache, fatigue, lethargy, dizziness, insomnia, drowsiness, muscle pain, muscle cramps, rash, itching, fever, swelling, thrombocytopenia, anemia, increased blood pressure, urinary incontinence, and polyuria have been reported.

This medication should be stored in a sealed container to prevent air infiltration and kept at room temperature between 1 to 30 degrees Celsius. This helps maintain the medication's efficacy over time.

Appearance

Red, double-convex, round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle