Union Donepezil Tablets 23 mg (Donepezil Hydrochloride Hydrate)

Adult dose

This medication should be taken once daily just before bedtime, without regard to meals. The initial recommended dose of Donepezil Hydrochloride is 5 mg once daily. After 4 to 6 weeks of taking 5 mg, the clinical response can be assessed, and it may be increased to 10 mg. When increasing to 10 mg daily, attention should be paid to gastrointestinal adverse reactions. It should be taken at least 10 mg once daily for a minimum of 3 months.

This medication contains Donepezil Hydrochloride Hydrate as the active ingredient and is used for the treatment of Alzheimer's-type dementia symptoms. This medication should not be given to certain patients. For example, individuals allergic to this medication or its components, women who are pregnant or may become pregnant, and those with lactose intolerance or inherited lactose metabolism disorders should not take this medication. Patients with heart diseases or heart conduction disorders should be cautious when taking this medication as bradycardia or arrhythmia may occur. Patients taking non-steroidal anti-inflammatory analgesics or have a history of peptic ulcers should be careful as symptoms may worsen due to increased gastric acid secretion and enhanced gastrointestinal motility. Patients with asthma or obstructive pulmonary disease should also be cautious, as bronchoconstriction and increased mucus secretion may worsen symptoms. Patients with extrapyramidal disorders, such as Parkinson's disease, may experience worsening of motor symptoms from this medication. Additionally, this medication contains Tartrazine (Yellow No. 4), and those allergic or sensitive to this ingredient should be cautious. Various adverse reactions may occur while taking this medication, such as fainting, bradycardia, heart block, gastrointestinal bleeding, liver dysfunction, cerebrovascular disorders, and movement disorders in severe cases. Mild adverse reactions may frequently include nausea, vomiting, diarrhea, loss of appetite, dizziness, insomnia, headaches, and fatigue. The occurrence of adverse reactions may increase, particularly at high doses, so patients should be closely monitored when increasing the dosage. This medication is not approved for other forms of memory disorders besides dementia, and treatment should be conducted under the supervision of a physician experienced in this area. This medication can affect heart conduction, so patients with heart diseases require monitoring, including an electrocardiogram. It is recommended that women who are pregnant or breastfeeding do not use this medication. This medication can interact with various drugs, so if other medications are being taken, consult a physician or pharmacist. In case of overdose, serious symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, requiring immediate medical attention, and Atropine can be used as an antidote. This medication should be kept out of reach of children, and transferring it to other containers is discouraged to maintain quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, high fever with severe rash, blisters, peeling skin, painful mucous membranes in the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough+fever accompanied respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, consciousness disturbances, visual disturbances, paralysis, and urinary issues.

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• lethargy
• dizziness
• insomnia
• hallucinations

This medication should be stored in a tightly sealed container to prevent air exposure and ideally kept at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

Red, biconvex, round film-coated tablet

Package unit

30 tablets/bottle