Donepezil 23 mg Tablet (Donepezil Hydrochloride Hydrate)

Adult dose

This medication is taken once daily just before bedtime, and can be taken independently of food. The initial recommended dose of Donepezil Hydrochloride is 5 mg once daily. For 4 to 6 weeks, 5 mg is administered and clinical response is evaluated before it can be increased to 10 mg. When increasing to 10 mg, caution should be exercised for gastrointestinal adverse reactions. For a minimum of 3 months, 10 mg is taken once daily.

This medicine should not be used by women who are allergic to certain ingredients, or are pregnant or nursing. Patients with genetic issues such as lactose intolerance should not take this medication. Caution is required for those with heart disease or cardiac conduction disorders, as this medication may affect heart rhythms. Patients with a history of peptic ulcers or those taking non-steroidal anti-inflammatory drugs should closely monitor their gastrointestinal symptoms. Patients with a history of asthma or chronic obstructive pulmonary disease may experience worsened symptoms when using this medication, so careful consideration is needed. Patients with extrapyramidal disorders such as Parkinson's disease should be cautious as this medication may worsen symptoms. This drug contains Tartrazine (Yellow No. 4), and those allergic to this ingredient should be careful. This medication may lead to serious side effects such as cardiac rhythm disturbances, gastrointestinal bleeding, liver dysfunction, cerebrovascular problems, and movement disorders, so if any unusual symptoms occur, consultation with a physician is necessary. Some patients may frequently experience side effects such as nausea, vomiting, diarrhea, dizziness, and insomnia. While used for dementia treatment, the effectiveness of the medication varies from person to person, hence regular evaluation and monitoring by a physician is necessary. In cases of heart disease or when taking specific medications, the risk of side effects may increase due to interactions with this drug, and patients must inform their doctor or pharmacist. Pregnant or nursing women are advised not to take this medication, and if it is absolutely necessary, should consult with a healthcare professional and discontinue breastfeeding. The safety for children has not been established, so it should not be used in pediatric patients. In cases of overdose, severe nausea, vomiting, respiratory distress, and muscle weakness may occur, requiring immediate treatment at a medical facility. This medication should be stored in a place out of reach of children, and it is recommended not to transfer it to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, breathing abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination problems

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• lethargy
• dizziness
• insomnia
• hallucinations

This medication should be stored in a tightly sealed container to prevent air and moisture infiltration. It is also recommended to store it at room temperature, avoiding direct sunlight, between 1°C and 30°C.

Appearance

Red, double convex, round film-coated tablet

Package unit

30 tablets/bottle