Pitasthan Tablet 1 mg (Pitavastatin Calcium Hydrate)

Adult dose

For adults, the usual initial dosage is 1 to 2 mg of Pitavastatin Calcium once daily. If the LDL-cholesterol reduction effect is insufficient, the dose may be increased to a maximum of 4 mg per day. The dosage should be adjusted based on LDL-cholesterol levels, treatment goals, and patient response at intervals of 4 weeks or more.

Child dose

For pediatric patients (10 to 16 years) with heterozygous familial hypercholesterolemia, take 1 mg of Pitavastatin Calcium once daily. If the LDL-cholesterol reduction effect is insufficient, the dose may be increased to a maximum of 2 mg per day.

This medication should not be administered to patients with known allergies to certain ingredients. Patients with active liver disease or persistently elevated liver function test results should also avoid this medication. Patients with severe liver disorders or biliary obstruction should not be given this drug, nor should it be used in patients taking cyclosporine. Individuals with myopathy, pregnant women, women who may become pregnant, and nursing mothers should not use this medication. It should also not be administered to patients with genetic issues such as lactose intolerance. Patients with impaired renal function or a history of liver disorders should use this medication with caution. In particular, co-administration with fibrates or niacin should be avoided due to the risk of muscle damage and worsening renal function. Caution is also advised when used in elderly or pediatric patients, particularly in cases of myasthenia. Unusual symptoms such as muscle pain, weakness, abdominal pain, rash, itching, etc. may occur while taking this medication, so it is essential to consult a doctor immediately if any symptoms arise. Regular liver function tests should be performed, and if liver abnormalities are found, the treatment should be discontinued. This medication can cause serious muscle damage known as rhabdomyolysis; therefore, if muscle-related symptoms arise, stop taking it immediately. There are many drug interactions, particularly with cyclosporine, fibrates, niacin, erythromycin, etc., thus increasing the risk of renal function deterioration and muscle damage; caution should be exercised. Pregnant women or those who may become pregnant should not use this medication, and it should be discontinued immediately if pregnancy is confirmed during treatment. In children, this medication should be administered with great care only under the guidance of a specialist for the treatment of familial hypercholesterolemia, and safety in children under the age of 10 has not been established. This medication should be kept out of the reach of children, stored in its original container to prevent misuse or degradation in quality.

Serious side effects

• Urticaria
• severe swelling (edema)
• liver dysfunction
• jaundice
• rhabdomyolysis
• acute renal failure
• severe allergic reactions
• thrombocytopenic purpura
• severe swelling or urinary abnormalities
• severe skin adverse reactions

Mild side effects

Abdominal pain, fatigue, itching, rash, muscle pain, headache, weakness, dry mouth, indigestion, abdominal bloating, constipation, stomatitis, vomiting, loss of appetite, glossitis, nausea, gastric discomfort, diarrhea, thrombocytopenia, granulocytopenia, leukopenia, eosinophilia, leukocytosis, globulin elevation, palpitations, skin tenderness, flushing, arthralgia, edema, blurred vision, photophobia, hearing loss, hematuria, increased uric acid levels, and elevated serum potassium and phosphorus.

This medication should be stored in a tightly closed container that protects from light, and it is safe to keep at room temperature between 1 to 30 degrees Celsius. Storing it this way can maintain the drug's effectiveness and prevent degradation.

Appearance

White round film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle