Amplin 10 mg (Empagliflozin)

Adult dose

The recommended dose for this medication is 10 mg once daily for monotherapy or additional combination therapy with insulin and other antihyperglycemic agents. If additional blood sugar control is needed with good tolerance, the dose can be increased to 25 mg once daily. It can be taken without regard to meals, and the tablet should be swallowed whole. If a dose is missed, it should be taken as soon as remembered, but do not take two doses in one day.

This medication should not be administered to certain patients. Firstly, patients who are allergic to the active ingredient or any component of this medication should not take it. Secondly, it should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Thirdly, it is not administered to patients with severely impaired kidney function or end-stage renal disease, and those undergoing dialysis. Fourthly, since it contains lactose, patients with lactose intolerance or galactose intolerance, as well as those with glucose-galactose malabsorption syndrome should not take this medication. Caution is required when administering this medication to patients with decreased kidney function. If kidney function falls below a certain level, dosage adjustments may be necessary or treatment may need to be stopped. It is not used in patients with end-stage renal disease or those on dialysis as its effectiveness cannot be expected. Regular monitoring of kidney function is essential to observe any changes. In patients with mild to moderate heart failure, caution is advised, and it is not recommended for patients with severe heart failure. There is a risk of hypoglycemia when used in conjunction with insulin or medications that promote insulin secretion, and dosage adjustments of insulin may be necessary when used with these medications. Various adverse reactions may occur during the use of this medication. The most common adverse reactions include hypoglycemia, genital infections, urinary tract infections, increased urination, and decreased fluid volume. Particularly, hypoglycemia can occur more frequently when combined with insulin or sulfonylureas. Additionally, severe metabolic acidosis such as ketoacidosis can rarely occur, in which case treatment should be stopped immediately, and evaluation and treatment by medical personnel are required. This medication is not used for the treatment of type 1 diabetes. Elderly patients, especially those over 75 years of age, are at a higher risk for fluid volume loss complications such as dehydration or hypotension and require caution. This medication may increase the risk of genital fungal infections, so patients with a history of fungal infections should be particularly cautious. Caution is advised when driving or operating machinery due to the risk of hypoglycemia. Particularly, if used in conjunction with insulin or sulfonylureas, extra care should be taken. Women who are pregnant or planning to become pregnant should not take this medication, and treatment should be stopped immediately upon confirmation of pregnancy. It is also recommended for breastfeeding women to stop breastfeeding while taking this medication. The safety and efficacy of this medication in patients who are children or adolescents, specifically those under 18 years of age, have not been established, and it should not be used in this population. In cases of overdose, no specific toxicity symptoms have been reported; however, appropriate treatment should be provided based on clinical condition. This medication should be kept out of reach of children, and transferring it to other containers should be avoided to maintain quality and safety.

Serious side effects

Hives, angioedema, ketoacidosis, urosepsis, pyelonephritis, perineal necrosis, liver damage (liver abnormalities), heart failure, hypoglycemia (significant hypoglycemia when used with sulfonylureas or insulin), severe edema or urinary abnormalities, severe allergic reactions, severe skin abnormal reactions, respiratory problems

Mild side effects

• Hypoglycemia
• vulvovaginitis
• balanitis
• other genital infections
• rash
• skin itching
• increased urination
• increased serum lipids
• increased serum creatinine
• decreased glomerular filtration rate

This medication may be sensitive to air and moisture, so it should be kept in a tightly closed container. It is best stored at room temperature between 1 and 30 degrees Celsius. This will help maintain its effectiveness safely.

Appearance

Light yellow, double convex, round film-coated tablet

Package unit

30 tablets/bottle