Jardiance 25 mg (Empagliflozin)

Adult dose

The recommended dosage of this medication for monotherapy and additional combination therapy with insulin and other hypoglycemic agents is 10 mg once daily. If good tolerance is exhibited but additional blood sugar control is required, the dosage may be increased to 25 mg once daily. It can be administered regardless of meals, and the tablet should be swallowed whole. If a dose is missed, take it as soon as remembered, but do not take two doses on the same day.

This medication should be avoided in certain patients. First, individuals with allergies to the active ingredient or any component of this medication should not use it. Second, it should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Third, patients with severely impaired kidney function, specifically those with a glomerular filtration rate of less than 30 mL/min/1.73m2 or those on dialysis due to end-stage renal disease, should not take this medication. Fourth, since it contains lactose, patients with genetic metabolic disorders such as lactose intolerance or galactose intolerance should also avoid this medication. Caution is needed when administering this medication to patients with slightly impaired kidney function. It is advisable not to initiate treatment with this medication in patients with a glomerular filtration rate of less than 60 mL/min/1.73m2, and doses may need to be adjusted or discontinued in patients already receiving it. This medication should not be used in patients with end-stage renal disease or those on dialysis, as the effectiveness is unlikely to be realized. In patients with heart failure who are classified as mild to moderate (NYHA class I-II), it should be used with caution, and it is not recommended for those who are classified as severe (NYHA class III-IV). When this medication is used in conjunction with insulin or sulfonylureas, which stimulate insulin secretion, the risk of hypoglycemia may increase, necessitating dose adjustments. Potential side effects during the use of this medication include hypoglycemia, genital infections, increased urination, urinary tract infections, decreased fluid volume, and increased serum creatinine. Particularly, hypoglycemia may occur more frequently when combined with insulin or sulfonylureas, so caution should be exercised. Genital infections may occur more frequently in women and are mostly mild in nature. If urination becomes frequent, consult a doctor for any discomfort. This medication can rarely induce serious ketoacidosis; therefore, immediate medical attention should be sought if symptoms such as vomiting, abdominal pain, or difficulty breathing occur. Elderly patients and those at risk of fluid volume loss should be cautious of dehydration or hypotension, and the use of this medication can be temporarily suspended if necessary. This medication can cause serious urinary infections such as urosepsis and pyelonephritis, necessitating prompt treatment for any signs of infection. Pregnant or breastfeeding women should avoid the use of this medication, and if pregnancy is confirmed, it should be discontinued immediately. The safety and efficacy of this medication in children under 18 have not been established. No specific toxicity has been reported in the event of overdose, but appropriate treatment may be required depending on the clinical situation. This medication should be kept out of reach of children, and it is advisable to avoid transferring it to other containers. Caution is needed during driving or operating machinery due to the risk of hypoglycemia. Regular kidney function tests should be conducted during the course of this medication, and if any abnormal signs are noted, immediate consultation with medical personnel is necessary.

Serious side effects

• Urticaria
• angioedema
• ketoacidosis
• urosepsis
• pyelonephritis
• perineal necrosis
• severe edema
• liver dysfunction (jaundice)
• severe allergic reactions
• serious adverse drug reactions

Mild side effects

• Vulvovaginal candidiasis
• vulvitis
• balanitis and other genital infections
• hypoglycemia
• itching
• rash
• increased urination
• increased serum lipids
• increased serum creatinine
• decreased glomerular filtration rate

This medication should be stored in a tightly closed container to avoid exposure to air or moisture, and it is best stored at a temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain its efficacy for a longer period.

Appearance

Pale yellow, biconvex, oval, film-coated tablet

Package unit

30 tablets/bottle