Widiang 25 mg Tablets (Empagliflozin)

Adult dose

The recommended dose of this medication is 10 mg once daily for monotherapy or additional combination therapy with insulin and other blood glucose-lowering agents. If 10 mg of this medication is well tolerated and additional glycemic control is required, the dose may be increased to 25 mg once daily. This medication can be administered regardless of meals, and the tablet should be swallowed whole. If a dose is missed, take it as soon as remembered, but do not take double doses in one day.

This medication should not be used by individuals allergic to the active ingredient or any of its components. It should not be administered to patients with type 1 diabetes or diabetic ketoacidosis. This medication should also not be used in patients with severely impaired kidney function, end-stage renal disease, or those undergoing dialysis. Patients with lactose intolerance or congenital lactose malabsorption should avoid this medication due to the lactose it contains. Patients with mildly impaired kidney function may need dose adjustment when taking this medication, and discontinuation is required if kidney function deteriorates further. Some heart failure patients have limited experience with this medication, so caution is needed, and it is not recommended for patients with severe heart failure. When this medication is used in conjunction with insulin or insulin secretagogues, the risk of hypoglycemia may increase; therefore, dosage adjustment may be necessary in such cases. During the course of treatment, patients should be vigilant for hypoglycemia symptoms, especially when combined with insulin or sulfonylureas, as hypoglycemia can occur. There is a possibility of urinary tract infections or genital infections, so if any infection symptoms appear, immediate consultation with a healthcare provider is advised. Increased urination may occur, which can cause discomfort. Hypotension or dehydration may result from fluid volume loss, so caution is particularly advised for elderly patients or those with low blood pressure. Rarely, severe metabolic abnormalities such as ketoacidosis can occur; patients should seek immediate medical attention if symptoms such as nausea, vomiting, abdominal pain, or shortness of breath occur. This medication is not recommended for use during pregnancy, and it should be discontinued if pregnancy is confirmed. Breastfeeding women should stop nursing while taking this medication, as it may affect the nursing infant. Children under 18 years old should not use this medication as its safety and efficacy have not been established. No specific toxicity has been reported in case of overdose, although appropriate treatment may be required depending on clinical condition. This medication should be kept out of the reach of children and should not be transferred to another container. Caution is required when driving or operating machinery due to the risk of hypoglycemia. Serious side effects such as limb amputation have been reported rarely, so diabetic patients should pay attention to foot care. Rare infectious diseases such as perineal necrotizing fasciitis may occur, so if there is pain or abnormal sensations in that area, immediate medical consultation is required. This medication may interact with other drugs, so patients should inform their doctor or pharmacist about any medications they are taking.

Serious side effects

Urticaria, angioedema, ketoacidosis, urosepsis, pyelonephritis, perineal necrotizing fasciitis, angioedema, deep vein thrombosis, acute kidney injury, acute cholecystitis, autoimmune hepatitis, severe allergic reactions, severe skin reactions, respiratory problems, liver dysfunction (jaundice), serious neurological symptoms, severe swelling or urination abnormalities

Mild side effects

• Hypoglycemia
• itching
• rash
• increased urination
• urinary tract infections
• decreased fluid volume
• increased serum creatinine
• decreased glomerular filtration rate
• thirst
• headache

This medication should be stored in a tightly closed container to prevent exposure to air and moisture. The safe storage temperature is between 1 and 30 degrees Celsius at room temperature. Proper storage will maintain the medication's efficacy and prevent deterioration.

Appearance

Light yellow, oval, film-coated tablet with a biconvex shape

Package unit

30 tablets/bottle