Jardiance 10 mg (Empagliflozin)

Adult dose

The recommended dose of this medication for monotherapy and additional combination therapy with insulin or other hypoglycemics is 10 mg once daily. If the patient has good tolerance to the 10 mg dose and requires additional blood sugar control, the dosage may be increased to 25 mg once daily. When this medication is used in combination with sulfonylureas or insulin, dosage reduction of sulfonylureas or insulin may be considered to reduce the risk of hypoglycemia.

This medication should not be used in patients who are allergic to the active ingredient or any component of this medication. It should not be administered to patients with type 1 diabetes or diabetic ketoacidosis. This medication is not used in patients with severely impaired renal function or end-stage kidney disease, as well as those undergoing dialysis. Since this medication contains lactose, patients with genetic metabolic disorders such as lactose intolerance or galactose intolerance should not take it. Patients with mild renal impairment should be administered this medication with caution and renal function must be monitored before administration and regularly thereafter. For patients with severe heart failure, this medication is not recommended, while mild patients should use it cautiously. When used together with insulin or sulfonylureas, the risk of hypoglycemia may increase, so dosage adjustments may be required. During administration, patients should carefully observe for symptoms such as hypoglycemia, infections, increased urination, urinary tract infections, or decreased fluid volume, among other side effects. Particular attention should be given to severe infection symptoms such as genital infections and necrotizing fasciitis, and related symptoms require immediate consultation with medical personnel. This medication can induce ketoacidosis, so if symptoms such as vomiting, abdominal pain, or breathing difficulties occur, immediate medical attention is required. Elderly patients or those at risk of fluid loss should take precautions against dehydration and low blood pressure, and may temporarily discontinue use if necessary. Patients taking this medication should use alternative methods for monitoring blood sugar levels, as 1,5-AG tests are unreliable. Women who are pregnant or planning to become pregnant should avoid this medication, and breastfeeding women should refrain from taking it. Children under 18 years of age should not use this medication as its safety and efficacy have not been established for this age group. There have been no reports of specific toxic symptoms from overdose, but clinical condition should be meticulously monitored, and appropriate treatment should be provided as necessary. Store this medication out of the reach of children, and do not transfer it to other containers for safety. This medication may have a slight impact on driving or operating machinery, especially for patients at risk of hypoglycemia, so caution is advised. Diabetes patients should pay attention to routine foot care and it is important to consult medical personnel regarding the possibility of lower limb amputation.

Serious side effects

Hives, angioedema, necrotizing fasciitis, ketoacidosis, urosepsis and pyelonephritis, severe edema or urination issues (including urinary retention), asthma attacks, serious allergic reactions (hives, angioedema), severe skin reactions (including rash), liver issues (jaundice symptoms are not explicitly stated but reports of liver damage exist), severe neurological symptoms (headaches, reported strokes), respiratory problems

Mild side effects

• Hypoglycemia
• vulvovaginal candidiasis
• vulvar vaginitis
• balanitis and other genital infections
• increased urination
• rash
• itching
• increased serum lipids
• increased serum creatinine
• decreased glomerular filtration rate

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius. By doing so, the medication's efficacy can be well maintained, ensuring safe use.

Appearance

Light yellow, double-sided, convex, round film-coated tablet

Package unit

30 tablets/bottle