Sitamono Tablet 50 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dosage

This medication is administered as a once-daily dose of 100 mg, either as monotherapy or in combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustments are necessary based on renal function. - For patients with mild renal impairment (eGFR 60 or more and less than 90): no dosage adjustment required - For patients with moderate renal impairment (eGFR 45 to less than 60): no dosage adjustment required - For patients with moderate renal impairment

This medication may cause severe allergic reactions; therefore, if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, discontinue use immediately and seek medical attention. While taking this medication, symptoms of acute pancreatitis, which is inflammation of the pancreas, may occur; if there is severe abdominal pain or vomiting, notify the healthcare provider immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and also should not be administered to those with known allergies to this drug or its components. Patients with impaired renal function should have their dosage adjusted and regularly undergo renal function tests. Hypoglycemia may occur when this medication is used alone or in combination with other diabetes medications, so it is important to be well aware of hypoglycemia symptoms, especially when taken with insulin or sulfonylureas. During treatment with this medication, symptoms such as headache, upper respiratory tract infection, nasopharyngitis, diarrhea, nausea, etc. may occur; patients should consult a physician if the symptoms are severe or persistent. Women who are pregnant or breastfeeding are advised not to take this medication, and safety in children under 18 has not been established. Elderly patients should have dosage adjustments and renal function tests due to the potential for impaired renal function. In the case of overdose, seek medical attention immediately for appropriate treatment; this medication may be partially removed via hemodialysis. Furthermore, if patients experience severe joint pain or skin blisters during treatment with this medication, they must inform their doctor immediately; discontinuation and treatment may be necessary. Finally, this medication has relatively few drug interactions, but consultation with healthcare providers for appropriate monitoring is advised when taken concurrently with cyclosporine or digoxin.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylaxis, severe hypersensitivity reactions, Stevens-Johnson syndrome, exfoliative skin conditions, acute pancreatitis (hemorrhagic or necrotizing, fatal/non-fatal), difficulty breathing, acute renal failure, severe and disabling arthralgia, bullous pemphigoid, jaundice (including increased liver enzymes), cardiac arrest, pneumonia, diabetes complications, metabolic acidosis, falls, rhabdomyolysis

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• diarrhea
• nausea
• constipation
• myalgia
• limb pain
• back pain
• pruritus

This medication should be stored in a tightly sealed container that does not allow air to penetrate, preferably between 1 degree to 30 degrees Celsius at room temperature. Proper storage will help maintain the drug's efficacy for a longer period.

Appearance

A film-coated tablet that is round, biconvex, and light apricot in color

Package unit

28 tablets/box [14 tablets/pity *2]