Neocita Tablet 25mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg, with a maximum daily dose of 100 mg. It can be taken regardless of meals. Dosage adjustment for patients with renal impairment: 1. For mild renal impairment (eGFR 60-90 mL/min/1.73 m2), no dosage adjustment is necessary. 2. For moderate renal impairment (eGFR 45-60 mL/min/1.73 m2), no dosage adjustment is necessary.

This medication may cause serious allergic reactions in some patients; if symptoms such as rash, difficulty breathing, or swelling of the face or neck occur, discontinue use immediately and consult a physician. Pancreatitis, which is inflammation of the pancreas, may occur during the use of this medication; if sudden abdominal pain, nausea, or vomiting occurs, visit a hospital immediately. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication. Patients with decreased kidney function may need a dosage adjustment; therefore, it is crucial to have kidney function tests regularly before and during treatment. During the use of this medication, side effects such as upper respiratory infections, rhinitis, headaches, and diarrhea may occur; if symptoms are severe, consult a doctor. There may be an increased risk of hypoglycemia if this medication is taken with other blood sugar-lowering agents, particularly insulin or sulfonylureas, so blood sugar levels should be monitored closely. If severe joint pain or skin blisters or rashes occur while taking this medication, inform a physician immediately, and if necessary, the medication may be discontinued. It is recommended that pregnant or nursing women do not use this medication, and safety for children under 18 years has not been established. Elderly patients may have decreased kidney function, necessitating dosage adjustments and kidney function tests. In the case of overdose, gastrointestinal removal of the medication and clinical monitoring, including an ECG, are necessary, and some removal may occur through hemodialysis. This medication has minimal drug interactions, but caution is needed when taken with certain medications, so inform your physician of any other drugs being used.

Serious side effects

• Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor → severe allergic reaction
• Severe rash with high fever, blisters, skin peeling, pain of oral/ocular mucosa → severe skin abnormal reaction
• Shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough + fever → respiratory issues
• Yellowing of the skin or eyes (jaundice), extreme lethargy → liver abnormalities (jaundice)
• Sudden

Mild side effects

• Upper respiratory infection
• rhinitis
• headache
• constipation
• vomiting
• muscle pain
• limb pain
• back pain
• itching
• thrombocytopenia

This medication should be stored in a sealed container to prevent air and humidity exposure, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent degradation.

Appearance

Pink, round, bilaterally convex film-coated tablet

Package unit

28 tablets/box [(14 tablets/PTPX2)]