Lipiduet Tablet 10/40 Milligrams

Adult dosage

This medication is administered once daily regardless of meals. In the case of primary hypercholesterolemia, it is administered in the range of 10/10mg to 10/80mg per day, with a recommended initial dose of either 10/10mg or 10/20mg per day. For patients requiring a greater reduction in LDL cholesterol (more than 55%), a recommended initial dose is 10/40mg per day. Lipid levels should be checked at intervals of more than 2 weeks after administration.

This drug can rarely cause a serious side effect called rhabdomyolysis, which can lead to damage to the kidneys due to the breakdown of muscle tissue. Therefore, patients showing severe myopathy symptoms or those with risk factors that may affect kidney function should suspend or discontinue this medication. This drug should not be administered to patients with allergies to the active or inactive ingredients, those with severe liver dysfunction, muscle diseases, pregnant women or those who may become pregnant, nursing mothers, patients taking certain antiviral medications, or those with lactose intolerance. Precautions should be taken when administering this medication to patients with a history of alcohol dependence or liver disease, moderate to severe liver dysfunction, kidney dysfunction, hypothyroidism, genetic muscle disease history, or elderly patients with risk factors for myopathy. If muscle-related symptoms such as muscle pain, muscle weakness, fatigue, or fever occur during treatment, consult a doctor immediately and blood tests should be conducted to check for muscle damage if necessary. Liver function abnormalities can occur; therefore, liver function tests should be done before and during treatment, and if liver enzyme levels continuously rise, the use of this drug should be discontinued or the dosage adjusted. Pregnant or nursing women should not take this medication, and women of childbearing age should use appropriate contraception while taking this medication. The safety and efficacy of this medication in children have not been established, and its use is not recommended. Caution is advised when administering this drug to elderly patients considering the risk of myopathy, although dosage adjustments are generally not necessary. This drug may interact with other medications, thus caution is needed when taken alongside certain antibiotics, antifungals, antivirals, immunosuppressants, and fibrates. Consultation with a doctor or pharmacist is recommended. In case of overdose, there is no specific antidote; treatment should be symptomatic and supportive, and monitoring of liver function and muscle damage is necessary. This drug should be stored out of reach of children and should not be transferred to other containers.

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, difficulty breathing or breathing discomfort, asthma attacks, respiratory distress with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Muscle pain
• abdominal pain
• nausea
• diarrhea
• headache
• cough
• dizziness
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be kept in a tightly sealed container as it is sensitive to air and moisture. Additionally, it should be stored at a cool temperature below 30 degrees Celsius to maintain its efficacy.

Appearance

White to off-white, oval, biconvex, film-coated tablet

Package unit

10 bottles/PPT, 3 PPT/box [30 tablets/box (10 tablets/PPT x 3)]