Ezetimibe and Atorvastatin Tablets 10/40 Milligrams

Adult dosage

This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10mg to 10/80mg daily. A starting dose of 10/10mg or 10/20mg daily is recommended. For patients requiring more significant reduction in LDL cholesterol (55% or more), a starting dose of 10/40mg daily is recommended. After starting treatment or adjusting the dosage, measurements of blood lipid levels should be taken at intervals of two weeks or more.

This medication is used to lower blood cholesterol levels and carries a risk of muscle abnormalities. If severe muscle pain or muscle weakness occurs, a physician should be consulted immediately. There is a risk of kidney impairment due to muscle damage, so caution is needed in patients with kidney disease or risk factors. Those allergic to ingredients in this medication, individuals with severe liver dysfunction, or those with muscle diseases should not take this medication. Women who are pregnant, may become pregnant, or are breastfeeding should also not use it. Since liver function abnormalities may occur, regular liver function tests should be conducted before and during treatment. There may be interactions with other medications, especially those that affect liver metabolism, so caution is needed when used together. Individuals who consume excessive alcohol or have a history of liver disease should use this medication with care. Elderly patients also have a higher risk of muscle abnormalities and should be cautious when taking it. Dizziness may occur when driving or operating machinery, so caution is advised. In case of overdose, there is no specific antidote, thus treatment according to symptoms and testing for liver function and muscle enzymes are necessary. This medication is not recommended for children as its safety and efficacy have not been established. Any unusual symptoms or discomfort during usage should be reported immediately to healthcare professionals for consultation.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

• Dizziness
• cough
• abdominal pain
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain
• hyperkalemia
• bronchitis

This medication should be stored in a tightly closed container to avoid exposure to air and moisture. It is advisable to keep the storage temperature between 1 degree and 30 degrees Celsius at room temperature.

Appearance

White to light white, biconvex film-coated rectangular tablets

Package unit

30 tablets/PTP (10 tablets/PTP x 3)