Vigat Tablet 10/40 Milligrams

Adult dosage

This medication is administered once daily, regardless of meals. An initial dosage of 10/10 mg or 10/20 mg daily is recommended. For patients needing greater reduction of LDL-cholesterol (more than 55%), an initial dosage of 10/40 mg daily is recommended. The recommended dosage for patients with homozygous familial hypercholesterolemia is 10/40 mg or 10/80 mg daily. The dosage range for this medication is 10/10 mg to 10/80 mg daily.

This medication carries a risk of serious muscle problems, so any symptoms such as muscle pain or weakness should be reported to a physician immediately. Patients who may develop issues with kidney function due to serious infections, hypotension, major surgeries, trauma, or severe metabolic abnormalities should pause or discontinue use of this medication. Individuals with a known allergy to this medication, severe liver disease, muscle disorders, women who are pregnant or may become pregnant, and nursing mothers should not take this medication. Additionally, patients with certain genetic issues such as lactose intolerance should not use this medication. Patients with alcoholism or poor liver function, those with kidney dysfunction, or hypothyroid patients at high risk for myopathy should use this medication with caution. The risk for muscle problems may increase when this medication is taken with other specific drugs; patients should consult with their doctor to adjust the dosage or change medications if necessary. Liver function tests should be performed regularly during treatment with this medication, and any symptoms indicative of liver dysfunction (e.g., nausea, vomiting, fatigue) should be reported to a physician immediately. Women who are pregnant or may become pregnant and those who are nursing should generally avoid this medication. The safety and efficacy of this medication in children have not been established, therefore it is not recommended for pediatric patients. Caution is advised in the elderly due to the increased risk of myopathy, though dosage adjustments are typically not necessary. In the case of overdose, no specific antidote is available; treatment should be symptomatic and supportive, including liver function and muscle-related tests. Dizziness may occur while taking this medication; caution should be exercised when driving or operating machinery.

Serious side effects

Hives, severe swelling (including angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances.

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• joint pain
• muscle weakness
• musculoskeletal pain
• hyperkalemia

This medication should be stored in a tightly closed container to protect it from exposure to air, at room temperature between 1°C and 30°C. It is important to avoid direct sunlight or high temperatures and to keep it out of reach of children.

Appearance

White, biconvex, rectangular film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP X 3)]