Intojet Tablet 10/40 mg

Adult dosage

This medication should be taken once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg once daily, with an initial dose of either 10/10 mg or 10/20 mg recommended. For patients requiring more significant (over 55%) reduction in LDL cholesterol, an initial dose of 10/40 mg once daily is recommended. After starting treatment or adjusting the dosage, lipid levels should be monitored at intervals of more than 2 weeks.

This medication can cause a rare side effect known as rhabdomyolysis, which can affect the muscles. This poses the risk of rapid deterioration of kidney function; thus, patients should inform their physician immediately if they experience severe muscle pain or weakness. In particular, patients at risk due to severe infections, hypotension, major surgery, trauma, metabolic disorders, endocrine problems, electrolyte imbalances, or uncontrolled seizures may need to temporarily suspend or discontinue the use of this medication. Patients allergic to any ingredient in this medication, those with severe liver impairment, those with muscle diseases, pregnant women or those who may become pregnant, nursing mothers, individuals taking certain antiviral medications, and those with lactose intolerance should not take this medication. Patients with a history of alcohol dependence or liver disease, significant liver dysfunction, impaired kidney function, hypothyroidism, a family history of muscle diseases, or previous experiences of muscle toxicity with similar medications, as well as elderly patients over 70 years of age, should use this medication with caution. This medication may cause side effects such as muscle pain, abdominal pain, or increased liver enzymes, and regular liver function and muscle-related tests should be conducted. If symptoms are severe or test results are abnormally high, discontinuation of the drug may be necessary. Furthermore, this medication may affect liver function, so liver function tests must be conducted before and during treatment, and administration should stop immediately if symptoms of liver damage appear. Pregnant or nursing women should not take this medication, and women of childbearing age should use appropriate contraception while taking it. Safety and efficacy in children have not been established, so it is not recommended, and caution is needed in elderly individuals due to the risk of myopathy. This medication may interact with various drugs, and if other medications are being taken, it is essential to consult with a physician or pharmacist, especially when combined with certain antibiotics, antivirals, antifungals, or immunosuppressants. In case of overdose, there is no specific antidote; therefore, symptomatic treatment and supportive care may be necessary, along with monitoring liver function and muscle enzyme levels. Lastly, dizziness may occur while taking this medication, so caution should be exercised when driving or operating machinery.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning-like headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Muscle pain
• abdominal pain
• increased liver enzymes
• dizziness
• cough
• nausea
• joint pain
• muscle weakness
• musculoskeletal pain
• hyperkalemia

This medication may be sensitive to air and moisture, hence it should be stored in a tightly closed container. It is crucial to maintain the storage temperature between 1 degree and 30 degrees Celsius to safely preserve the efficacy of the medication over time.

Appearance

White or whitish oblong film-coated tablet

Package unit

Alu-Alu - 30 tablets/box [10 tablets/Alu-Alu*3], bottle - 30 tablets/bottle