DuoPito 10/10 mg

Adult dosage

This medication is administered once a day regardless of meals. The dosage range is 10/10 mg to 10/80 mg once daily. The recommended starting dose is 10/10 mg or 10/20 mg once daily. For patients requiring significant LDL-cholesterol reduction, the recommended starting dose is 10/40 mg once daily. After starting treatment or adjusting the dose, lipid levels should be checked after an interval of more than 2 weeks to adjust the dose.

This medication carries a risk of serious muscle problems, so if severe muscle pain or weakness occurs suddenly, the patient should inform their doctor immediately. Especially if there are conditions such as severe infections, major surgery, trauma, or severe metabolic abnormalities or electrolyte imbalances, this medication may need to be temporarily discontinued. Women who are pregnant or nursing, or individuals with known allergies to any of its components, severe liver dysfunction, or muscle diseases should not use this medication. Also, patients with certain liver diseases or abnormally high serum liver enzyme levels should not be administered this medication. Patients with a history of alcohol abuse or liver disease, those with impaired kidney function or a history of hypothyroidism or muscle disease should use this medication with caution. Elderly patients over 70 years old are also at a higher risk for muscle-related issues, so caution is advised. Moreover, patients taking fibrate class medications should be careful as well. Regular liver function tests should be performed during treatment with this medication, and if any symptoms of liver dysfunction appear, treatment should be stopped immediately. Women who are pregnant or may become pregnant should use appropriate contraceptive methods, and if pregnancy is confirmed, this medication should be discontinued immediately. Nursing mothers are also advised against taking this medication for the safety of their infants. This medication has not been established as safe and effective in children and is not recommended. While elderly patients are at a higher risk for muscle-related problems and should exercise caution during use, dosage adjustment is not strictly necessary. Patients with impaired kidney function should be closely monitored for the risk of muscle issues. When taking this medication with other drugs, the risk of side effects may increase due to interactions, particularly with medications metabolized in the liver or those that can affect muscles, so patients should consult their doctor beforehand. Patients may experience dizziness, muscle pain, or abdominal pain during treatment, and caution should be exercised when driving or operating machinery. In case of overdose, there is no specific antidote, and appropriate care and supportive treatment should be sought based on symptoms, while monitoring liver function and muscle damage.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, peeling skin, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning bolt headache, seizures, confusion, visual disturbances, paralysis, urine

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be stored in a tightly closed container to prevent air or moisture from entering, and it should be kept in a cool place below 30 degrees Celsius to maintain its efficacy.

Appearance

White to off-white, biconvex, oval film-coated tablet

Package unit

30 tablets/box [10 tablets/PVC × 3]