Procyta 25 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered 100 mg once daily in monotherapy or combination therapy, with a maximum daily dosage of 100 mg. It can be taken regardless of meals. For patients with renal impairment, adjustments are not required for mild to moderate renal impairment (estimated glomerular filtration rate [eGFR] 45 or greater but less than 90). For moderate renal impairment with eGFR between 30 and 45, administer 50 mg once daily.

This medication may cause severe allergic reactions in some patients; if skin rash, difficulty breathing, or swelling of the face or neck occurs, discontinue use immediately and consult a physician. While taking this medication, serious pancreatic inflammation known as pancreatitis may occur; if abdominal pain, nausea, or vomiting occurs, visit a hospital immediately. Patients with type 1 diabetes or diabetic ketoacidosis should not use this medication, and patients with hypersensitivity to this medication or its components should also refrain from use. Patients with impaired kidney function need to have their dosage adjusted, so regular kidney function tests should be conducted, and the medication should be taken as directed by a physician. Taking this medication with other blood glucose-lowering agents may increase the risk of hypoglycemia, so caution is advised regarding hypoglycemia symptoms when used in combination with insulin or sulfonylureas, and dosage adjustments may be necessary. While taking this medication, side effects such as headache, upper respiratory infection, nasopharyngitis, diarrhea, and abdominal pain may occur; if symptoms are severe or persistent, consult healthcare providers. If severe joint pain or blistering skin disorders occur, stop taking the medication immediately and consult a doctor. It is advisable for pregnant or breastfeeding women to avoid using this medication, and safety and efficacy have not been established in children or adolescents under 18 years of age. Elderly patients may risk impaired kidney function, thus kidney function should be monitored before and after taking this medication to ensure caution. In case of overdose, visit a medical facility immediately for appropriate treatment, and this medication can be partially removed via hemodialysis. This medication has minimal drug interactions, but caution is necessary when used with specific medications, so it's important to inform the doctor or pharmacist of any other medications being taken. If unusual reactions or uncomfortable symptoms occur while taking this medication, it's essential to consult healthcare providers promptly.

Serious side effects

Urticaria, angioedema, anaphylaxis, Stevens-Johnson syndrome and other exfoliative skin diseases, acute pancreatitis, acute renal failure, severe and disabling arthralgia, bullous pemphigoid, rhabdomyolysis, pneumonia, diabetes complications, metabolic acidosis, cardiac arrest, hypoglycemia, severe hypoglycemia

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• constipation
• vomiting
• headache
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and it's best kept at room temperature between 1°C and 30°C. Proper storage maintains the medication's effectiveness and prevents deterioration.

Appearance

Pink, round, biconvex film-coated tablet

Package unit

28 tablets/box [14 tablets/PTP*2]