Nanubia Tablets 25 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

For monotherapy or combination therapy, the recommended dose is 100 mg once daily, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustment is necessary based on kidney function. - For mild renal impairment (eGFR 60 to <90): No dosage adjustment needed. - For moderate renal impairment (eGFR 45 to <60): No dosage adjustment needed. - For moderate renal impairment.

This medication can cause rare but serious allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after taking this medication, stop taking it immediately and consult a healthcare professional. This medication can cause pancreatitis, which is inflammation of the pancreas, so notify a healthcare professional immediately if symptoms such as abdominal pain, vomiting, or nausea occur. Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication, nor should individuals with hypersensitivity to this medication or its ingredients. Patients with reduced kidney function should have their dosages adjusted, and regular kidney function tests are important. Hypoglycemia can occur while taking this medication, especially when used with insulin or sulfonylureas, so blood glucose levels should be monitored closely and dosages adjusted as necessary. This medication can cause serious side effects such as severe joint pain or blistering dermatitis, so consult a doctor immediately if any of these symptoms occur. Pregnant or breastfeeding women are advised not to take this medication, and safety and efficacy have not been established in children or adolescents under 18 years of age. Older patients may have reduced kidney function, so it is necessary to periodically check kidney function before and during treatment with this medication. In case of an overdose, general symptomatic treatment is performed, and renal dialysis may be required to remove the medication if necessary. This medication generally has less interaction with other hypoglycemic agents, but caution is needed when used with certain medications, so it is important to inform healthcare professionals of any other medications being taken.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes, blisters, skin peeling, mucosal pain in the mouth/eyes, Stevens-Johnson syndrome, acute pancreatitis, shortness of breath or difficulty breathing, asthma attack, respiratory issues accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), thyroid issues

Mild side effects

• Upper respiratory infections
• nasopharyngitis
• constipation
• vomiting
• headache
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is recommended to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Pink, round, biconvex film-coated tablet

Package unit

28 tablets / box [(14 tablets / PTPX2)]