Newstazet A Tablets 10/10 mg

Adult dosage

This medication should be taken once daily, regardless of meals. The dosage range is 10/10 mg to 10/40 mg per day. For the initial dose, 10/10 mg or 10/20 mg is recommended. For patients requiring a greater reduction in LDL cholesterol, dosage adjustments may be made. After initiating treatment or adjusting the dose, lipid levels should be checked at intervals of more than 2 weeks.

This medication is a lipid-lowering agent containing atorvastatin and ezetimibe, used to lower blood cholesterol levels. Before taking this medication, be cautious as symptoms such as muscle pain or weakness may occur, especially in patients at risk for severe myopathy or rhabdomyolysis. Immediate consultation with a physician is necessary if symptoms like muscle pain, muscle cramps, muscle weakness, fever, or fatigue appear, and it may be necessary to check muscle enzyme levels via blood tests. Furthermore, this medication can affect liver function, so liver tests are essential before starting and during treatment. If liver enzyme levels significantly exceed the normal range, the use of the medication should be stopped or the dosage adjusted. This medication may be contraindicated or used with caution in patients with specific diseases or those taking other medications. For instance, patients with active liver disease, unexplained elevated liver enzymes, muscle disorders, pregnant or breastfeeding women, and those taking certain antiviral or fibrate medications should not take this drug. Elderly patients or those with reduced kidney function may have an increased risk of myopathy, so caution is needed, and dosage adjustments or regular monitoring is recommended. Additionally, this medication can interact with various drugs, so it is essential to inform the physician or pharmacist if other medications are being taken. Particularly, caution and dosage adjustments are needed when co-administering with CYP3A4 inhibitors, cyclosporine, certain antibiotics, antiviral drugs, and fibrate medications. Women who are pregnant or may become pregnant should not take this medication, and women of childbearing age should use appropriate contraceptive methods while on this drug. Nursing mothers should also avoid using this medication. This medication is not recommended for children, as its safety and efficacy have not been established. In case of overdose, specific antidotes are not available, so appropriate treatment and supportive therapy according to symptoms should be provided, monitoring liver function and muscle enzyme levels. Finally, this medication should be stored out of the reach of children, and it is advisable not to transfer it to another container.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary retention

Mild side effects

• Diminished sensation
• abnormal sensation
• hypertension
• increased ALT
• increased GGT
• nasopharyngitis
• cough
• itching
• dizziness
• diabetes

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain storage temperatures between 1 to 30 degrees Celsius. This helps to ensure the medication's efficacy and safety.

Appearance

White oval film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP*3]