Medication info
Utojet Tablet 10/40mg

Utojet Tablet 10/40mg

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium›43.4mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
(주)유유제약
Appearance
White oval film-coated tablet
Packaging
30 tablets/box [10 tablets/PTP (×3)], 30 tablets/bottle
Approval status
Active

MFDS item code 202100192 · Approved 2021.01.08 · Insurance code 644503270

Summary

Main use
Improvement of cholesterol and lipids in hypercholesterolemia (primary, mixed) and dyslipidemia
Who uses it
Adults
Adult dosage
This drug is administered once daily, regardless of meals. The dosage range is 10/10mg to 10/40mg per day. A starting dose of 10/10mg or 10/20mg is recommended. For patients requiring more significant reductions in LDL cholesterol, the dosage may be adjusted. After starting treatment or adjusting the dosage, lipid levels should be checked at intervals of at least 2 weeks for dosage adjustment.

Ingredients

Manufacturer
(주)유유제약

Efficacy & effects

Improvement of cholesterol and lipids in hypercholesterolemia (primary, mixed) and dyslipidemia

  • Primary hypercholesterolemia
  • dyslipidemia
  • elevated total cholesterol
  • LDL cholesterol
  • Apo B protein
  • triglycerides
  • non-HDL cholesterol
View approved original text

This drug is used as an adjunct to diet for lowering elevated total cholesterol, LDL cholesterol, Apo B protein, triglycerides, and non-HDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia, and for raising HDL cholesterol levels. Particularly, it is administered in cases of abnormally elevated blood lipid levels in conjunction with diet to aid in the prevention of cardiovascular disease. Before starting this medication, it is essential to identify other conditions that may cause dyslipidemia, such as diabetes and hypothyroidism, and to provide necessary treatments. Additionally, to ensure safe treatment, regular checks of various lipid levels are required, and especially during acute coronary events, rapid lipid testing is crucial. This drug is used alongside an appropriate diet and is helpful in treating hypercholesterolemia and dyslipidemia when improvements are difficult with diet alone.

Dosage and Administration

Adult dosage

This drug is administered once daily, regardless of meals. The dosage range is 10/10mg to 10/40mg per day. A starting dose of 10/10mg or 10/20mg is recommended. For patients requiring more significant reductions in LDL cholesterol, the dosage may be adjusted. After starting treatment or adjusting the dosage, lipid levels should be checked at intervals of at least 2 weeks for dosage adjustment.

Precautions

This drug can cause a rare side effect of rhabdomyolysis, which may lead to acute renal failure. Therefore, if symptoms of severe muscle pain or muscle weakness occur, inform a doctor immediately. This medication should not be administered to patients with known allergies to the active ingredients or excipients, severely impaired liver function, muscle diseases, pregnant women or those who may become pregnant, nursing mothers, patients taking specific antiviral agents, and patients with lactose intolerance. Patients with a history of liver disease or alcohol abuse, those with impaired kidney function, hypothyroidism, elderly patients, and those at high risk of myopathy should use this drug cautiously with regular tests and monitoring. During treatment with this drug, side effects such as liver dysfunction, muscle pain, muscle weakness, digestive disorders, headaches, dizziness, hypertension, diabetes, etc., may occur, so consult a doctor if any abnormal symptoms arise. This drug may interact with other medications, so it is essential to inform the doctor when taking drugs that affect liver metabolism or those that influence muscles, and dosage adjustments or cessation of use may be necessary. Pregnant or nursing women should not use this medication, and women of childbearing age should employ appropriate contraceptive methods while taking it. The safety and efficacy of this drug in children have not been established, therefore it is not recommended. Elderly individuals should be cautious due to the increased risk of myopathy while using this medication. This drug should not be used in patients with severely impaired liver function or active liver disease. In case of overdose, as there is no specific antidote, appropriate treatment and supportive care based on symptoms should be provided, and regular liver function and muscle-related tests should be conducted. This medication should be kept out of reach of children, and transferring to other containers should be avoided.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headaches, thunderclap headache, seizures, confusion, vision changes, paralysis, urinary changes

Mild side effects

  • Diminished sensitivity
  • abnormal sensation
  • nasopharyngitis
  • cough
  • itching
  • dizziness
  • diabetes
  • headache
  • hypertension
  • fatigue
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  • malaise
  • chest pain
  • peripheral edema
  • fever
  • hyperglycemia
  • hypoglycemia
  • weight gain
  • loss of appetite
  • constipation
  • abdominal bloating
  • indigestion
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • oropharyngeal pain
  • epistaxis
  • insomnia
  • nightmares
  • myalgia
  • arthralgia
  • limb pain
  • muscle cramps
  • joint swelling
  • back pain
  • neck pain
  • muscle fatigue

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a closed container to prevent exposure to air and moisture, and it is best kept at room temperature between 1 to 30 degrees Celsius. By doing so, the effectiveness of the medication is maintained and it can be used safely.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP (×3)], 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.