Donggwang Pitavastatin Tablet 1 Milligram (Pitavastatin Calcium)

Adult dose

In adults, the usual starting dose of pitavastatin calcium is 1 to 2 milligrams once daily. If the LDL cholesterol lowering effect is insufficient, the dose may be increased to a maximum of 4 milligrams daily. The dosage should be appropriately adjusted every 4 weeks or longer intervals based on LDL cholesterol levels, treatment goals, and patient response.

Child dose

Pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 16) should take 1 milligram of pitavastatin calcium once daily. If LDL cholesterol lowering effect is insufficient, a maximum of 2 milligrams per day may be increased.

This medication should not be used in patients allergic to certain components or with impaired liver function. Patients with active liver disease or persistently elevated liver enzyme levels, severe liver impairment, or bile flow problems should not take this medication. Also, patients taking cyclosporine, those with muscle disorders, pregnant or potentially pregnant women, and breastfeeding women should not use this medication. Patients with genetic issues sensitive to lactose should also avoid this medication. Patients with renal impairment or a history of liver impairment, as well as those who consume excessive alcohol, should use this medication with caution. In particular, caution is needed when co-administered with fibrates or niacin due to an increased risk of muscle damage. Elderly patients and children also require special attention when using this medication. If symptoms such as muscle pain, weakness, abdominal pain, rash, or itching occur while taking this medication, consultation with a physician should occur immediately. Liver function abnormalities may arise, so regular liver function tests should be conducted before and during treatment. Rarer side effects such as thrombocytopenia, liver dysfunction, renal function abnormalities, or neurological symptoms can occur, hence careful monitoring is necessary. This medication is prescribed for hypercholesterolemia treatment; therefore, it is preferable to try dietary and exercise interventions thoroughly before administration. While taking this medication, blood lipid levels should be monitored regularly to assess treatment effectiveness, and discontinuation should occur if ineffective. Since this medication is mainly metabolized in the liver, dosage adjustments are necessary for liver impaired patients, and careful attention is required for muscle-related side effects when increasing the dose. Interactions may occur between this medication and others, particularly when co-administered with cyclosporine, fibrates, niacin, or erythromycin, so caution is warranted. Pregnant or breastfeeding women should not take this medication, and potentially pregnant women must confirm their pregnancy status before use. Children should only be carefully administered under a physician's guidance for familial hypercholesterolemia, with close monitoring of physical activity levels and muscle condition. This medication should be kept out of reach of children and stored in its original container to maintain quality.

Serious side effects

Hives, angioedema, rhabdomyolysis, myopathy, liver dysfunction, jaundice, thrombocytopenia, severe allergic reactions, significant edema or urinary abnormalities, serious neurological symptoms, acute renal failure, interstitial lung disease, difficulty breathing, severe skin adverse reactions, serious allergic reactions, liver abnormalities (jaundice), edema with increased blood pressure, acute worsening of renal function, seizures, visual disturbances, paralysis

Mild side effects

• Abdominal pain
• rash
• fatigue
• paralysis
• itching
• headache
• muscle pain
• stiffness
• drowsiness
• insomnia

This medication may be sensitive to light, so it should be stored in a container that blocks light. Additionally, it is recommended to store the medication at room temperature between 1 to 30 degrees Celsius. This storage helps to maintain the drug's efficacy and safety.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle