Medication info

Hyalipclover Cream

OTC medicationCream
Ingredient · strength
Acyclovir›50mg / 1gHydrocortisone›10mg / 1g
Manufacturer / importer
(주)에이프로젠바이오로직스
Appearance
White or pale yellow cream
Packaging
10g / tube
Approval status
Active

MFDS item code 202008048 · Notified 2020.11.20

Summary

Main use
Initial treatment effect for recurrent herpes labialis
Who uses it
Adults
Adult dosage
Apply an adequate amount that can sufficiently cover the border of the affected area 5 times a day for 5 days. Treatment should be initiated as soon as initial symptoms and signs appear.

Ingredients

Manufacturer
(주)에이프로젠바이오로직스

Efficacy & effects

Initial treatment effect for recurrent herpes labialis

  • Recurrent herpes labialis
View approved original text

The use of antiviral agents is very important for the initial treatment of recurrent herpes labialis. These medications help prevent the progression of symptoms, promote lesion healing, and alleviate pain. Initiating treatment early can reduce the severity of symptoms. It can also decrease the frequency of recurrences and assist in rapid recovery. Therefore, antiviral agents are used for the initial treatment of recurrent herpes labialis.

Dosage and Administration

Adult dosage

Apply an adequate amount that can sufficiently cover the border of the affected area 5 times a day for 5 days. Treatment should be initiated as soon as initial symptoms and signs appear.

Precautions

This medication should not be used in patients with certain infections, especially bacterial infections such as tuberculosis or syphilis, fungal infections such as candidiasis or tinea, and viral infections such as shingles or chickenpox. Additionally, individuals with allergies or hypersensitivity to this medication's components, those with severe immune system damage like bone marrow transplant recipients or AIDS patients, patients with eczematous otitis externa with a perforated tympanic membrane, individuals with ulcers or severe burns, those with perioral dermatitis or common acne, rosacea patients, nursing mothers, individuals under 18 years of age, and those with a history of myocardial infarction should also avoid this medication. This medication should not be applied to sensitive areas such as the eyes, nose, mouth, or genitals, and concomitant use with certain medications should be avoided. It is advisable to avoid breastfeeding during use, and women who are pregnant or may become pregnant, as well as the elderly, should consult with a physician or pharmacist before use. Side effects such as dryness of the skin, peeling, burning sensation, numbness, redness, inflammation may occur, and if such symptoms arise, use should be discontinued immediately and professional advice should be sought. With prolonged or extensive use, side effects such as skin atrophy, vasodilation, acne, and skin infections may occur, so caution is needed. This medication should only be used for a maximum of 5 days, and if symptoms do not improve or worsen, professional consultation should be sought immediately. Moreover, this medication is intended solely for the treatment of herpes labialis around the lips and should not be used for any other skin conditions or for infection prevention.

Side effects and when to seek care immediately

Mild side effects

  • Dryness
  • skin peeling
  • temporary burning sensation
  • numbness
  • redness
  • pigmentation
  • inflammatory symptoms
  • contact dermatitis
  • folliculitis
  • pimples
Show 23 more
  • skin irritation
  • pain
  • fever
  • burning sensation
  • rash
  • erythema
  • flushing
  • itching
  • dry skin
  • pustular dermatitis
  • allergic contact dermatitis
  • heat rash
  • hives
  • wound deterioration
  • pressure sores
  • pustulosis
  • steroid-induced acne
  • skin atrophy
  • telangiectasia
  • purpura
  • steroid-induced rosacea
  • perioral dermatitis
  • tinea

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture, preferably at room temperature between 1 degree and 30 degrees Celsius. Proper storage maintains the medication's effectiveness for a longer period.

Appearance and packaging

Appearance

White or pale yellow cream

Package unit

10g / tube

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

  • QCan I apply it around my eyes?

    The product manual states that when used on the skin of the eyelids, it may cause an increase in intraocular pressure, glaucoma, and blurred vision. The approved indication is for herpes labialis, so do not apply it around the eyes arbitrarily and consult a doctor.

    Answers 1 · 2026.09.14

  • QIs it okay to apply when I feel a blister forming on my lips?

    This cream is used for the early treatment of recurrent herpes labialis, and it is advised to start using it as soon as initial symptoms appear. For adults, apply it sufficiently to the edges of the affected area 5 times a day for 5 days.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.