Tenegliptin Tablets 20 mg (Teneligliptin Hydrochloride Hydrate)

Adult dose

The recommended dosage of this medication, whether as monotherapy or in combination therapy, is 20 mg once daily. It can be taken regardless of meals.

This medication should not be administered to certain patients. It is not suitable for patients with hypersensitivity to this drug or for type 1 diabetes patients who require insulin therapy, or those in diabetic ketoacidosis or coma. Additionally, it is not recommended for patients with severe infections or those undergoing surgery, or for patients with severe trauma who may require insulin therapy. The safety of this drug has not been established in patients with severe liver dysfunction, so it should be used with caution. In patients with mild to moderate heart failure, there is limited experience, so caution is needed, and it is advisable not to use it in patients with severe heart failure. Patients using sulfonylureas or insulin are at risk of hypoglycemia, so caution is necessary. Patients exhibiting high-risk conditions for hypoglycemia such as pituitary dysfunction, adrenal insufficiency, malnutrition, irregular meals, strenuous exercise, and excessive alcohol consumption should also be careful. It is preferable to avoid use in patients with a history of abdominal surgery or bowel obstruction, severe bradycardia, arrhythmias, or heart diseases that may cause QT interval prolongation. The risk of acute pancreatitis has been reported with this medication, so if severe abdominal pain or vomiting occurs, immediate diagnosis and treatment by medical professionals are necessary. During treatment with this drug, symptoms of hypoglycemia may occur, so it is essential to fully understand the symptoms and management of hypoglycemia. Especially when taken in conjunction with insulin or sulfonylureas, the risk of hypoglycemia may increase, necessitating dosage adjustments. This medication may cause side effects such as liver dysfunction, constipation, dizziness, skin rash, and joint pain, so any unusual symptoms should be discussed with a physician. The safety of this drug in pregnant or lactating women has not been established, and its use is not recommended. Safety and efficacy in pediatric patients have also not been confirmed. Elderly patients may have reduced physiological function, so patient status should be carefully monitored during administration. In the case of overdose, general symptomatic treatment is advised, and additional treatment such as ECG monitoring may be necessary based on the situation. This medication should be kept out of the reach of children, and transferring it to another container is not recommended as it may negatively affect its quality. Finally, this medication may interact with other diabetes treatment medications or specific drugs, so it is essential to inform healthcare providers of any other medications being taken. If severe joint pain or skin blisters develop while taking this medication, immediate notification to healthcare professionals and appropriate treatment are necessary.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attack, cough with fever and respiratory abnormalities, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headaches, thunderclap headache, seizures, altered consciousness, vision abnormalities, paralysis, urinary issues

Mild side effects

• Dizziness
• constipation
• abdominal bloating
• abdominal discomfort
• nausea
• abdominal pain
• flatulence
• stomatitis
• gastric polyps
• colon polyps

This medication should be stored in a tightly closed container to protect it from air, and it should be kept at a temperature between 1 degree and 30 degrees Celsius. This storage method helps maintain the drug’s effectiveness and prevent degradation.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 60 tablets/bottle