Nebilet M Tablet 2.5 mg (Nebivolol Hydrochloride)

Adult dose

For the treatment of essential hypertension, administer 5 mg of Nebivolol orally once daily at the same time. For patients with renal impairment, the initial dose is 2.5 mg orally once daily, which can be increased to 5 mg if needed. For elderly patients (65 years and older), the initial dose is 2.5 mg orally once daily, which can be increased to 5 mg if necessary. For chronic heart failure, in elderly patients aged 70 and older, this medication should be administered to those without a history of acute heart failure in the past six weeks, and doses of diuretics, digoxin, ACE inhibitors, angiotensin II receptor blockers, and other cardiovascular medications should be stabilized at least 2 weeks prior to administration. The dosage should be gradually increased every 1-2 weeks until an optimal dose is reached based on the patient's condition, starting with 1.25 mg of Nebivolol once daily, and can be increased to 2.5 mg, 5 mg, and up to 10 mg once daily as needed. The maximum daily dosage is 10 mg. It can be taken with food.

This medication should not be used in patients with certain diseases or conditions. For example, it should not be administered to patients who are allergic to this medication, or to those with bronchial asthma, severe heart issues, severe liver or kidney function disorders, pregnant women or nursing mothers. Also, patients who are genetically lactose intolerant should not take this medication. Caution is required when administering this medication to patients with chronic lung disease, heart failure, diabetes, thyroid dysfunction, and the elderly. Side effects such as skin rash, vision problems, heart rhythm disorders, digestive issues, breathing difficulties, and fatigue may occur during the use of this medication, and medical consultation should be sought immediately if unusual symptoms arise. As this drug belongs to the beta-blocker category, it may be necessary to discontinue its use before surgery, and dosage adjustments may be needed. Additionally, this medication may interact with various other drugs, so it is essential to inform healthcare professionals about any other medications being taken. It is advisable not to take this medication during pregnancy or breastfeeding due to the risk of adverse effects on the fetus or newborn. Its safety and efficacy have not been confirmed in children under 18, so its use is not recommended in this age group. For the elderly, treatment should start at a lower dose with careful monitoring of their condition. In case of overdose, severe bradycardia, hypotension, and respiratory distress may occur, requiring immediate emergency treatment. Specialized treatment such as gastric lavage, administration of atropine, or use of pressor agents may be necessary for overdose.

Serious side effects

Urticaria, angioedema, chest tightness, difficulty breathing, bronchospasm, severe swelling, worsening heart failure, bradycardia, cerebrovascular disease, chronic myeloid leukemia, jaundice, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, markedly reduced urine output, generalized severe edema, edema associated with increased blood pressure

Mild side effects

• Rash
• vision impairment
• bradycardia
• AV block
• AV conduction delay
• hypotension
• heart failure
• intermittent claudication
• headache
• dizziness

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. Additionally, it should be kept away from extreme heat or cold, ideally stored at room temperature between 1° and 30° Celsius.

Appearance

White round tablet

Package unit

30 tablets/bottle, 300 tablets/bottle