Medi&Pen Injection (Acetaminophen)

Adult administration

Adults weighing 50 kg or more Administer 1000 mg of acetaminophen 4 times a day, with a minimum interval of 4 hours between doses. The maximum daily dosage should not exceed 4 grams. Pediatrics weighing 33 kg or more and adults weighing less than 50 kg 15 mg/kg of acetaminophen (this medication 1.5 ml/kg) per single administration, with a minimum interval of 4 hours between doses. The maximum daily dosage should not exceed 60 mg/kg or 4 grams.

Child administration

Pediatrics weighing 33 kg (approximately 11 years) or more The same as for pediatric patients weighing 33 kg or more and adults weighing less than 50 kg 15 mg/kg of acetaminophen (this medication 1.5 ml/kg) per single administration.

Care must be taken not to confuse milligrams and milliliters during administration. Overdose due to confusion can lead to serious poisoning or death. Once the patient is able to take medications orally, it is advisable to switch to appropriate analgesics as soon as possible. Be sure to check if other medications contain acetaminophen to avoid overdose. This medication can cause serious liver damage if the recommended dosage is exceeded, and symptoms of liver damage typically appear 4 to 6 days after administration. Immediate treatment is required if there are abnormalities in liver function. Patients with liver disease or impaired liver function must consult their doctor before taking this medication, and regular liver function tests are necessary when taking high doses for extended periods. Individuals who drink several glasses of alcohol daily must consult healthcare professionals before taking this medication, or else liver damage may occur. A serious skin reaction may rarely occur after taking this medication, so if a rash or hypersensitivity reaction develops, administration should be stopped immediately and healthcare professionals should be notified. Patients with hypersensitivity to acetaminophen or this medication, peptic ulcers, severe liver or kidney dysfunction, or severe heart function impairment should not take this medication. Patients with a history of asthma attacks triggered by non-steroidal anti-inflammatory drugs, those taking certain medications, or those who have consumed alcohol should also avoid this medication. Patients with liver disease, kidney disease, peptic ulcers, blood disorders, tendency to bleed, heart function impairment, hypersensitivity, bronchial asthma, elderly individuals, children, pregnant or nursing women, or those taking certain medications should use this medication cautiously and consult their healthcare professional adequately. Various adverse reactions such as fatigue, hypersensitivity reactions, hypotension, increased liver enzymes, blood disorders, neurological disorders, kidney failure, skin rash, have been reported in clinical trials and post-marketing experiences. When used in conjunction with certain medications, drug effects may change, or the risk of hepatotoxicity may increase, so it is essential to inform healthcare professionals about any medications currently being taken. This medication does not affect driving or operating machinery, and should not be mixed with other medications for use. Children and the elderly should take the minimum dosage and be monitored for adverse reactions, and patients with infections may take this medication alongside antibiotics as directed by a doctor. During pregnancy, the benefits and risks of this medication must be carefully evaluated before use, and while breastfeeding, a small amount is secreted into breast milk, but no adverse reactions have been reported. Patients with severely impaired kidney function should maintain a dosing interval of at least 6 hours. In cases of overdose, initial symptoms may include nausea, vomiting, loss of appetite, pallor, and abdominal pain, and in severe cases, can lead to liver damage, coma, or death; immediate medical attention is required for detoxification treatment. This medication should not be stored at temperatures above 30 degrees Celsius and should avoid refrigeration or freezing, and should be stored in external packaging. Before use, check for foreign substances or discoloration, and unused solution should be discarded as this is for single use only.

Serious side effects

Hives, severe swelling (edema), anaphylactic shock, liver abnormalities (including jaundice, fulminant hepatitis, liver necrosis, liver failure, increased liver enzymes), agranulocytosis, neutropenia, leukopenia, thrombocytopenia, acute kidney failure, acute generalized pustular rash, toxic epidermal necrolysis, Stevens-Johnson syndrome, shock, coma, angioedema, anaphylaxis, severe edema, thrombocytopenia, seizures, altered consciousness.

Mild side effects

• Fatigue
• hypotension
• increased liver transaminase levels
• neurological disorders
• maculopapular rash
• injection site reactions
• morbilliform rash
• similar to pemphigus reactions
• pustular rash
• nausea

This medication should be stored in a sealed container that does not allow air to enter, at room temperature between 1 and 30 degrees Celsius. By storing it this way, the medication's effects can be safely maintained.

Appearance

A transparent colorless to yellowish liquid in a plastic container for infusion.

Package unit

100 milliliters/box