Nexgliptin Tablet 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg, either as monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustments may be necessary based on renal function. - Mild renal impairment (eGFR 60–90 mL/min/1.73 m2): No dosage adjustment needed - Moderate renal impairment (eGFR 45–60 mL/min/1.73 m2): Dosage

This medication can occasionally cause serious allergic reactions, so if symptoms such as skin rash or difficulty breathing occur, stop taking it immediately and consult a physician. Additionally, if symptoms of pancreatitis such as severe abdominal pain, vomiting, or fever develop while taking this medication, seek medical attention immediately. Patients with type 1 diabetes or a history of allergic reactions to this medication should not use it. Patients with renal impairment need to adjust the dosage of this medication, so they should take it according to their physician's instructions. While taking this medication, symptoms of hypoglycemia may occur, especially if taken in conjunction with insulin or sulfonylureas, so caution is advised. If severe joint pain or symptoms of skin blistering occur, notify a physician immediately and discontinue use of the medication. Pregnant or breastfeeding women are advised not to take this medication, and safety in children under 18 years has not been established. Elderly patients should undergo regular kidney function tests because renal function may be decreased during use. In case of overdose, gastrointestinal decontamination and appropriate treatment such as ECG monitoring should be applied, and some drugs may be removed by hemodialysis. This medication may interact with other diabetes treatments or specific medications, so inform your physician or pharmacist about any other medications you are taking. It is important to consult medical personnel immediately if any abnormal symptoms occur.

Serious side effects

Severe hypersensitivity reactions (anaphylaxis, angioedema, urticaria), exfoliative skin conditions (Stevens-Johnson syndrome), acute pancreatitis (hemorrhagic or necrotizing), severe and disabling joint pain, bullous pemphigoid, acute kidney failure, pneumonia, diabetes complications, metabolic acidosis, cardiac arrest

Mild side effects

• Headache
• upper respiratory tract infection
• nasopharyngitis
• abdominal pain
• nausea
• diarrhea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly closed container that is well-ventilated and kept at room temperature between 1 and 30 degrees Celsius. Storing it this way helps to maintain the medication’s efficacy over time.

Appearance

Light orange, round, biconvex film-coated tablets

Package unit

30 tablets - 10 tablets/PTP[x3]