Xone A Tablet 5/160/20 mg

Adult dose

This medication is taken once daily, one tablet with water. It is recommended to take it at the same time each day (e.g. morning). The dosing of the amlodipine/valsartan combination and atorvastatin should be individualized based on efficacy and tolerability for each patient. For the amlodipine/valsartan combination, doses of 5/80 mg, 5/160 mg, or 10/160 mg may be used depending on patients whose blood pressure is not well controlled with monotherapy.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy and should be discontinued immediately upon confirmation of pregnancy. If muscle-related issues are suspected or if muscle enzyme levels rise significantly, the use of this medication should be stopped, as there is a risk of serious muscle damage leading to renal failure, requiring caution. This medication should not be administered to patients with certain diseases or conditions, such as those with severely impaired liver or kidney function, pregnant or breastfeeding women, or individuals with specific allergies. Patients with fluid or sodium depletion, hyperkalemia, renal artery stenosis, or those with kidney transplants should use this medication cautiously, with close monitoring before and during administration. Caution is needed when driving or operating machinery as dizziness or fatigue may occur. This medication can affect liver function, so patients with a history of liver disease should consult a doctor before taking it and undergo regular liver function tests. If symptoms of muscle pain, weakness, or fever occur, they should contact a doctor immediately, and discontinuation should occur if abnormalities are found in muscle enzyme testing. There may be interactions with other medications taken with this medication, so patients must inform their doctor or pharmacist of any other medications they are currently taking. Particularly, when taken with potassium-sparing diuretics or potassium supplements, potassium levels may dangerously rise, requiring periodic blood tests. This medication is not recommended for breastfeeding women, and atorvastatin is contraindicated during breastfeeding. Women of childbearing age should use appropriate contraception while taking this medication, and should consult their doctor if planning to become pregnant. While taking this medication, regular examinations are needed for symptoms of abnormal liver function, muscle issues, or changes in blood pressure. Anyone experiencing abnormal symptoms while on medication should consult medical personnel immediately.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral and ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination problems

Mild side effects

• Dry eyes
• nausea
• headache
• visual impairment
• anxiety
• dizziness
• drowsiness
• positional dizziness
• paresthesia
• lightheadedness

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. Moreover, it is advisable to keep the medication at room temperature between 1 Celsius and 30 Celsius, away from extreme heat or cold.

Appearance

Pale pink oval film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle