Posilojinjeong 5 mg (Dapagliflozin Anhydrous Mixture)

Adult dose

The recommended dose of this medication is 10 mg once daily for monotherapy and combination therapy with other antihyperglycemic agents such as insulin. For initial combination therapy: when there is no prior experience with diabetes medication, the doses are 5 mg once daily or 10 mg once daily when combined with metformin. This medication can be taken orally at any time of the day, regardless of food intake, and the tablets should be swallowed whole.

Child dose

The efficacy and safety of dapagliflozin in children under 18 years of age have not been established.

This medication should not be used in patients with allergic reactions to the main ingredient or excipients. Additionally, it should not be administered to patients with type 1 diabetes or diabetic ketoacidosis. Since it contains anhydrous lactose, it should not be used in patients with genetic problems such as galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. Patients on dialysis should also not take this medication. Patients with decreased fluid volume or renal impairment should use this medication cautiously. This medication can cause hypotension or deterioration of kidney function, so it is essential to closely check fluid status and kidney function before and after administration. Particularly, elderly patients or those on diuretics are at high risk for hypotension and should be cautious. This medication contains Yellow No. 4 and Yellow No. 5 coloring agents, so it should be administered with caution in patients with allergies or hypersensitivity to these components. Taking this medication may increase the risk of genital infections or urinary tract infections. If symptoms of infection appear, immediate consultation with healthcare professionals is required. Hypoglycemia symptoms may occur; therefore, when taking it along with insulin or sulfonylureas, dose adjustment may be necessary to reduce the risk of hypoglycemia. Dehydration or hypotension symptoms may arise due to decreased fluid volume, so if symptoms of dehydration occur, the use of this medication should be temporarily discontinued, and a doctor should be consulted. Rarely, serious infections such as perineal necrosis can occur, so if there is pain, swelling, redness, or discomfort around the genital area, immediate medical attention should be sought. Pregnant or breastfeeding women are advised not to use this medication, and its use should be discontinued if pregnancy is confirmed. The safety and efficacy of this medication in children have not been sufficiently established, so its use is not recommended. In case of overdose, there are no specific antidotes, so it is important to receive appropriate treatment according to the symptoms. This medication does not significantly affect driving or operating machinery, but caution is needed due to the risk of hypoglycemia.

Serious side effects

• Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor → severe allergic reaction
• Severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes → severe skin reactions
• Difficulty breathing or shortness of breath, asthma attacks, breathing issues associated with coughing + fever → respiratory problems
• Yellowing of the skin or eyes (jaundice), extreme lethargy → liver disorders (jaundice)
• Sudden and

Mild side effects

Vulvovaginitis, balanitis, urinary tract infection, fungal infection, hypoglycemia (especially when combined with insulin or sulfonylureas), decreased fluid volume (dehydration, hypovolemia, hypotension), dizziness, constipation, dry mouth, back pain, pain during urination, polyuria, nocturia, increased hematocrit, dyslipidemia, elevated serum creatinine, elevated blood urea, weight loss, itching, sweating, urticaria, muscle weakness, headache, cough, shortness of breath, edema, and

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is recommended to keep it at room temperature between 1 to 30 degrees Celsius. Storing it this way will preserve the medication's effectiveness and ensure safe use.

Appearance

Yellow, bilaterally convex, round film-coated tablet

Package unit

28 tablets/box [14 tablets/PTP x 2]