Champix Tablet 1 mg (Varenicline Salicylate)

Adult dose

After choosing a quit date, the patient should start taking this medicine 1 week before that date. Alternatively, smoking cessation may be started between day 8 and day 35 after starting this medicine. Take this medicine after a meal with plenty of water. The recommended dose of this medicine is as follows: after dose titration over 1 week, take 1 mg twice daily. Days 1–3 0.5 mg once daily Days 4–7 0.5 mg twice daily Day 8–end of treatment 1 mg twice daily For patients who cannot tolerate the adverse reactions of this medicine, the dose may be reduced temporarily or permanently. The treatment period is 12 weeks. For patients who successfully quit smoking with the first 12 weeks of treatment, it is recommended to continue taking this medicine for an additional 12 weeks to increase the likelihood of long-term abstinence. For patients who cannot or do not wish to stop smoking abruptly, consider gradually reducing smoking while taking this medicine. Within the first 4 weeks after starting this medicine, smoking should be reduced by 50% compared with before treatment; within the next 4 weeks, it should be reduced by a further 50%. Continue reducing smoking so that complete cessation is achieved by week 12. Continue taking this medicine for an additional 12 weeks for a total treatment period of 24 weeks. No dose adjustment is required in patients with mild (estimated creatinine clearance > 50 ml/min and ≤ 80 ml/min) to moderate (estimated creatinine clearance ≥ 30 ml/min and ≤ 50 ml/min) renal impairment. In patients with severe renal impairment (estimated creatinine clearance < 30 ml/min), the recommended starting dose of varenicline is 0.5 mg once daily. If needed, the maximum dose is 0.5 mg twice daily. In patients with end-stage renal disease receiving hemodialysis, if well tolerated, a maximum dose of 0.5 mg once daily may be administered. No dose adjustment is required in patients with hepatic impairment. In older patients, caution should be exercised when selecting the dose, as renal function is more likely to be reduced; monitoring renal function may be useful.

Child dose

Patients under 18 years of age: Use is not recommended.

This drug is used to treat nicotine addiction. When taking this drug, there may be psychiatric symptoms, such as depression, anxiety, and suicidal thoughts, so caution is needed. In particular, patients with a history of psychiatric disorders should be monitored more carefully, and if symptoms occur, they should consult a doctor immediately. Patients with allergies or hypersensitivity to this drug should not take it. Pregnant or breastfeeding women must consult a doctor before using this drug. Common side effects during treatment include nausea, headache, insomnia, and abnormal dreams, most of which are mild or temporary. This drug can also be used in patients with cardiovascular diseases, but if heart-related symptoms worsen, they should inform their doctor immediately. Caution should be taken while driving or operating machinery, as drowsiness or dizziness may occur. Additionally, alcohol consumption should be avoided or minimized while taking this drug. This drug is excreted through the kidneys, so patients with impaired kidney function may require dosage adjustments. In the case of overdose, there is no specific antidote, so appropriate treatment must be administered according to the symptoms. This drug should be kept out of reach of children, and it is safe to store it in its original container.

• suicidal ideation
• suicidal behavior
• suicide
• changes in behavior or thought
• depression
• mania
• mood changes
• psychosis
• aggressive behavior
• hallucinations

This drug may be sensitive to air or humidity, so it should be stored in a tightly sealed container. Additionally, it is safe to store it at room temperature, specifically between 1 to 30 degrees Celsius, away from extreme heat or cold.

Appearance

Light blue, bidirectional convex film-coated tablet

Package unit

28 tablets/box [14 tablets/Blister x 2]