Shinil Clarithromycin Tablet 250 mg

Adult dosage

○ Adults: The usual dose of clarithromycin is 250mg (potency) per dose twice daily. For severe infections, administer 500mg (potency) per dose twice daily. The usual duration of administration is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, administer 250mg (potency) per dose twice daily. Do not administer this drug to these patients for more than 14 days. ○ Mycobacterial infections: Administer 500mg (potency) of this drug per dose twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. ○ Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer this drug 500mg (potency) three times daily in combination with omeprazole 40mg once daily for 14 days, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose three times daily for 14 days (days 1～14), and administer omeprazole 40mg once daily for 28 days (days 1～28).

Children's dosage

○ Children 12 years and older: Same as adults ○ For children under 12 years, use clarithromycin dry syrup.

This medication should not be used by patients who are allergic to certain ingredients or have had hypersensitivity reactions to specific antibiotics. Additionally, patients with heart rhythm disorders or severe liver or kidney disease, as well as pregnant or nursing women, should not use this medication. Precaution should be taken with patients who are taking certain other medications, as there is a risk of cardiac arrhythmias or toxic reactions. Patients with reduced liver or kidney function should have their dosage adjusted, and elderly patients or those with heart disease should use this medication cautiously. Various side effects such as allergic reactions, gastrointestinal disturbances, liver function abnormalities, kidney issues, heart problems, or skin rash may occur; if symptoms arise, consult a physician immediately. To prevent the emergence of antibiotic-resistant organisms, use should be limited to the necessary duration, and it is important not to stop taking the medication arbitrarily, even if symptoms improve. Since this medication may interact with other drugs, inform your healthcare provider of any medications being taken, especially when combined with cardiovascular drugs, anticoagulants, diabetes medications, or immunosuppressants. This medication should not be used during pregnancy or breastfeeding, and if its use is unavoidable, breastfeeding should be discontinued. In children under 12 years old due to lack of experience in use, caution is advised and adjustments in dosage may be necessary for the elderly due to decreased kidney function. This medication may cause dizziness or confusion when driving or operating machinery; caution is advised. In cases of overdose, gastrointestinal symptoms or central nervous system abnormalities may occur, and immediate medical treatment is required. Store at room temperature, avoiding refrigeration and direct sunlight in a sealed container.

Shock, anaphylactic symptoms, dyspnea, convulsions, erythema, rash, itching, urticaria, skin erythema, angioedema, joint swelling, drug eruption, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, upper abdominal pain, convulsion type, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disturbances, decreased appetite, constipation, discoloration of stool, membrane colitis, hemorrhagic colitis, fever, cough, chest X-ray abnormalities, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, orientation disturbance, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug eruption associated with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, increased LDH, elevated ALP, increased total bilirubin, decreased appetite, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, myalgia, weakness, elevated CPK, increased myoglobin in blood and urine, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, taste disorder, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, tinnitus, hearing impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute pancreatitis, increased amylase, elevated AST, elevated ALT, increased BUN, thrombocytopenia, leukopenia, neutropenia, thrombocytosis, agranulocytosis, thrombocytopenia, anaphylactic reactions, angioedema, decreased appetite, insomnia, nervousness, noise sensitivity, psychotic disorder, states of confusion, abnormal dreams, movement disorders, non-vestibular dizziness, drowsiness, tremor, vestibular dizziness, hearing impairment, hearing loss, cardiac arrest, atrial fibrillation, ectopic contractions, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, abnormal liver function tests, cholestasis, elevated alanine aminotransferase, elevated aspartate aminotransferase, elevated gamma-glutamyl transferase, hepatocellular jaundice, vesicular dermatitis, hyperhidrosis, papular rash, acne, Henoch-Schönlein purpura, acute generalized pustular exanthema, muscle cramping, musculoskeletal rigidity, myopathy, elevated blood urea, venous thrombophlebitis at the injection site, pain at the injection site, inflammation at the injection site, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated blood alkaline phosphatase, elevated blood lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urine color abnormalities, changes in mental status, obsessive behavior, hypokalemia, hypoxemia

This medication should be stored at room temperature between 1 to 30 degrees Celsius. It is important to store it in a sealed container, away from direct sunlight.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle