Selmax Injection (Selenic Acid)

Adult dosage

In stable metabolism total parenteral nutrition (TPN), administer 20 to 40 μg of selenium per day (this product contains selenium 40 μg/mL).

Children's dosage

Inject 3 μg per kg of body weight per day. Monitor plasma selenium levels frequently for reference during the next administration.

This medication contains selenium and should not be used in patients with selenium toxicity. Toxicity may appear in case of overdose, so if any abnormal symptoms occur, use should be stopped immediately. Administering without dilution can lead to the possibility of phlebitis, so it must be diluted before administration. This medication is a stable solution, so it must be mixed before administration. Caution is required in patients with renal dysfunction and premature neonates, particularly due to the risk of toxicity associated with aluminum content. Rarely, pain or allergic reactions may occur during injection, so if these symptoms arise, immediate consultation with medical staff is necessary. If symptoms such as dermatitis, odor while sweating or breathing, hair loss, agitation, or vomiting occur, discontinue use and consult a professional. Before administration, visually check for precipitates or discoloration, and it is important to prepare in an aseptic condition. Selenium is affected by kidney and gastrointestinal function, so dosage should be adjusted in cases of renal dysfunction or gastrointestinal disorders. In transfusion patients, it is necessary to consider the amount of selenium and continuously monitor blood concentration. It should only be administered to pregnant women or women of childbearing potential when the therapeutic benefits outweigh the risks, as there have been reports of fetal malformations. Safety has not been established for breastfeeding women, and during medication administration, breastfeeding may need to be suspended or the drug discontinued. Chronic symptoms may appear with overdose, such as abnormal growth of nails and hair, dermatitis, gastrointestinal abnormalities, metallic taste, vomiting, and garlic odor. Acute overdose may result in severe vascular and pulmonary symptoms and can lead to death; immediate emergency care is necessary. In cases of overdose, gastric lavage, induced urination, and high-dose vitamin C administration are carried out, and in extreme cases, dialysis may be required to remove selenium. This medication should be kept out of reach of children, stored in a sealed container in a dry and room temperature environment, and used immediately after opening. Caution should be exercised as transferring to another container may pose the risk of accidents and quality deterioration.

Serious side effects

• Acute peripheral vascular collapse
• internal vascular congestion
• pulmonary hemorrhage
• congestion
• and edema
• gastric mucosal brick-red change.

Mild side effects

Pain during injection, rarely occurring allergic reactions, dermatitis, unpleasant odor while sweating or breathing, hair loss, agitation, vomiting, effects on nail and hair growth, oral abnormalities, gastrointestinal abnormalities, tension, depression, metallic taste, garlic odor from the mouth.

This medication should be stored in a sealed container to prevent air or moisture ingress, at a cool place between 15°C and 30°C. This way, the efficacy of the drug can be well maintained.

Appearance

A colorless and odorless transparent liquid contained in a colorless transparent vial injection.

Package unit

10 vials/box [10mL/vial x 10]