Nexrica Capsule 25 mg (Pregabalin)

Adult dose

This medication is pregabalin, administered orally, split into two doses daily, without regard to meals. 1. Neuropathic pain 1) Peripheral neuropathic pain Adults: A starting dose of 150 mg per day may be administered. After 3 to 7 days, it can be increased to 300 mg per day. If necessary, it can be titrated up to 600 mg per day at increments of 7-day intervals thereafter. 2) Central neuropathic pain

Child dose

Safety and efficacy data are insufficient for children under 12 years and adolescents aged 12-17, so administration is not recommended.

This medication may increase the risk of suicidal thoughts and behavior; therefore, mood or behavioral changes should be closely monitored during treatment. Patients with hypersensitivity to this medication, lactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not use it. Patients with diabetes should be cautious as weight gain may require adjustment of glucose control medications. If symptoms such as facial and oral swelling or upper airway swelling occur, this medication should be discontinued immediately. Elderly patients may experience side effects such as dizziness, drowsiness, or loss of consciousness more readily; caution is especially necessary at the beginning of treatment. If vision blurring or changes in eyesight occur during treatment with this medication, symptoms may improve or disappear, but caution is advised. Abrupt discontinuation of this medication may result in withdrawal symptoms such as insomnia, headache, nausea, and anxiety; therefore, it should be gradually reduced under a doctor's guidance. There is a risk of drug abuse or dependence; thus, patients with a history of drug abuse should use this medication with caution. Patients with reduced kidney function may require dosage adjustment, and cases have been reported where kidney function improved after discontinuation of this medication. Patients with heart failure should use this medication with caution, and those with cardiac conditions should consult their doctors. The risk of drowsiness and respiratory depression increases when combined with other central nervous system depressants or alcohol, so caution is necessary. In early pregnancy, there is a risk of congenital malformations; therefore, women who are pregnant or planning to become pregnant should definitely consult a doctor. Breastfeeding women should consider that this medication may pass into breast milk, weighing the benefits of treatment against breastfeeding. Caution is advised during activities such as driving or operating machinery, as dizziness or drowsiness may occur due to this medication. Severe skin reactions (such as Stevens-Johnson syndrome) have been reported rarely; if skin rash or unusual symptoms appear, discontinue the medication immediately and consult a healthcare provider. This medication should be kept out of reach of children, and it is safer not to transfer it to another container. In the case of an overdose, symptoms such as drowsiness, confusion, depression, and seizures may occur, so it is essential to visit a healthcare institution for appropriate treatment.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, difficulty breathing or dyspnea, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urinary issues.

Mild side effects

• Confusion
• disorientation
• irritability
• depression
• euphoria
• decreased libido
• insomnia
• depersonalization
• sexual dysfunction
• restlessness

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. It is recommended to maintain the storage temperature between 15 to 30 degrees Celsius.

Appearance

A hard capsule with a pale yellow upper part and a white lower part containing white powder.

Package unit

30 capsules/bottle