Rotajet Tablets 10/20 Milligrams

Adult dose

This medication is taken once daily regardless of meals. For primary hypercholesterolemia, it is started at 10/5 mg once daily, and the dosage can be adjusted after checking lipid levels at intervals of 4 weeks or more, if necessary. The maximum dosage is 10/20 mg per day.

This medication can rarely cause rhabdomyolysis, which can lead to serious kidney problems by damaging muscle tissue. Particularly, patients with compromised kidney function due to acute infections, hypotension, major surgery, trauma, metabolic abnormalities, seizures, etc., should pause or discontinue taking this medication. Individuals allergic to the active or inactive ingredients of this medication, those with severely impaired liver function, muscle disorders, those taking certain immunosuppressants, individuals with severe kidney impairment, and women who are pregnant or breastfeeding should not take this medication. Those at high risk for myopathy or rhabdomyolysis, for example, individuals with compromised kidney function, those with hypothyroidism, those with a family history of muscle disorders, those with a history of muscle toxicity from other statins or fibrate medications, alcoholics, and Asian patients should take this medication with caution. This medication contains lactose, so individuals with lactose intolerance or certain genetic metabolic disorders should avoid taking it. If muscle pain, muscle cramps, muscle weakness, fatigue, fever, etc., occur during the course of this medication, the patient must immediately inform a doctor and undergo examination, and in some cases, the medication may need to be discontinued. Liver function abnormalities may occur, so regular liver function tests should be conducted before and during use, and if liver enzyme levels are abnormally high, dose adjustment or discontinuation may be necessary. This medication may slightly elevate blood sugar levels, so patients at risk of diabetes must manage their blood sugar carefully. There may be interactions with other medications, so particularly if taking anticoagulants, fibrate medications, certain antibiotics, antifungals, or immunosuppressants, consult with a doctor or pharmacist. Pregnant women or those who may become pregnant must meticulously practice contraception while taking this medication, and if pregnancy is confirmed, they must immediately discontinue use. Breastfeeding women are also advised to avoid taking this medication and should consult with a doctor if necessary. Safety in children and adolescents has not been adequately established, so it is advised not to use it except in special cases. Elderly patients are at higher risk for myopathy and should take caution with use, although dose adjustments are generally not necessary. In the case of overdose, there is no specific antidote, so appropriate treatment based on symptoms and testing of liver function and muscle enzymes should be performed. This medication should be stored in a tightly closed container to prevent exposure to air or moisture, and it is recommended to maintain storage temperature between 1 and 30 degrees Celsius.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, sweating, pallor, severe rash with high fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attack, respiratory difficulties accompanied by cough+fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination.

Mild side effects

• Pharyngitis
• arthralgia
• headache
• ALT elevation
• AST elevation
• myalgia
• edema
• elevated blood bilirubin
• acneiform dermatitis
• pruritus

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is advisable to maintain storage temperatures at room temperature between 1 to 30 degrees Celsius.

Appearance

White to nearly white round film-coated tablets

Package unit

30 tablets/bottle, 30 tablets/box [10 tablets/PTP × 3]