Hanmim Sitaglipton 100 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

The dosage for this medication is 100 mg once daily as monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustments are needed based on renal function. - Mild renal impairment (eGFR 60~90 mL/min/1.73 m2): No dosage adjustment required - Moderate renal impairment (eGFR 45~60 mL/min/1.73 m2): Dosage adjustment required

This medication may rarely cause severe allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or lips occur after taking the medication, you should stop taking it immediately and consult a healthcare professional. This medication may cause a serious side effect known as pancreatitis, which is inflammation of the pancreas. If severe abdominal pain, vomiting, or loss of appetite occur during treatment, you should notify your doctor immediately. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and it should be avoided in individuals who are allergic to this medication or any of its components. Patients with reduced kidney function need dosage adjustments; thus, those with kidney disease or impaired renal function should always consult healthcare professionals beforehand. During treatment, symptoms similar to a cold such as headache, indigestion, diarrhea, etc. may occur, as well as symptoms of low blood sugar, so blood glucose monitoring must be cautious. Especially, when used in conjunction with insulin or sulfonylureas, the risk of hypoglycemia increases, hence it is necessary to frequently monitor blood glucose levels and adjust the dose if necessary. Severe joint pain or a rare side effect with blisters on the skin has been reported, and if these symptoms occur, you should consult a doctor immediately and stop taking the medication. It is advisable for pregnant or breastfeeding women not to take this medication, and safety for children or adolescents under 18 has not been established. Elderly patients may require dose adjustments and regular kidney function testing due to the possibility of reduced kidney function. In the case of overdose, as there is no specific antidote, you should visit a medical facility immediately for appropriate treatment and monitoring, and some medications may be removed through dialysis. This medication does not have significant interactions when taken with many other drugs; however, when taking certain medications, disclose to healthcare professionals and appropriate management is necessary. The cardiovascular safety of this medication has been confirmed; however, if any abnormal symptoms occur during use, you should immediately consult a healthcare professional.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylaxis, severe skin reactions (Stevens-Johnson syndrome, bullous pemphigoid, etc.), acute pancreatitis, difficulty breathing, severe allergic reactions, acute renal failure, severe and disabling joint pain, cardiac arrest, severe hypoglycemia, pneumonia, diabetic complications, metabolic acidosis, falls

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• abdominal pain
• nausea
• diarrhea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container that is not exposed to air, and it is advisable to maintain a temperature between 1 and 30 degrees Celsius. Proper storage maintains the drug's effectiveness and safety.

Appearance

Pale orange, round, biconvex film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP × 3]