Aycita Tablet 25 Milligrams (Sitagliptin Hydrochloride Monohydrate)

Adult dose

For monotherapy or combination therapy, administer 100 mg once daily, with a maximum daily dose of 100 mg. It can be taken without regard to meals. In patients with moderate renal impairment (glomerular filtration rate [eGFR] 30–45 mL/min/1.73 m²), administer 50 mg once daily. In patients with severe renal impairment (glomerular filtration rate [eGFR] 15–30 mL/min/1.73 m²) or those requiring hemodialysis or peritoneal dialysis,

This medication may cause rare but serious allergic reactions; therefore, if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after taking the medication, you should immediately stop taking it and consult a doctor. This medication may lead to serious pancreatitis; therefore, if symptoms such as abdominal pain, vomiting, or fever occur during use, you should inform a healthcare professional immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in those allergic to this medication or any of its components. Patients with decreased kidney function may experience delayed excretion of this medication, so dosage adjustment is necessary, and regular kidney function tests should be conducted. This medication may cause side effects such as cold symptoms, headaches, and upper respiratory infections in some patients when used alone, and there is an increased risk of hypoglycemia when used in combination with other diabetes medications. Particularly, when taken with insulin or sulfonylureas, hypoglycemic symptoms may occur more frequently, so blood sugar should be checked regularly, and dosages adjusted if necessary. This medication is not recommended for use during pregnancy, and nursing mothers should avoid taking it. It is advisable not to use this medication in children or adolescents under 18 years of age, as safety and efficacy have not been established. Elderly patients may have a higher likelihood of reduced kidney function, so careful dose adjustments and regular kidney function tests are necessary. In case of overdose, general emergency measures should be taken, and if necessary, some of the medication may be removed by hemodialysis. If symptoms such as joint pain or blistering on the skin occur during the course of taking this medication, you should immediately notify a doctor and consider discontinuing the medication. Additionally, this medication has relatively few interactions with other drugs, but blood concentration changes may occur with certain medications, so it is important to inform healthcare professionals of any other medications being taken.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, rash, exfoliative skin disease (including Stevens-Johnson syndrome), acute pancreatitis, severe joint pain with complications, bullous pemphigoid, acute renal failure, elevated liver enzymes, liver abnormalities (including elevated liver enzymes and liver abnormalities, though jaundice is not specified), pneumonia, diabetic complications, metabolic acidosis, cardiac arrest, rhabdomyolysis

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• constipation
• vomiting
• muscle pain
• limb pain
• back pain
• pruritus
• thrombocytopenia

Store this medication in a tightly sealed container to prevent air from entering. It is best to maintain a storage temperature between 1°C and 30°C at room temperature to preserve the medication's effectiveness.

Appearance

Pink, round, double-sided, convex film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP x 3]