Samsit Tablet 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered as a single therapy or in combination therapy at a dose of 100 mg once daily, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In cases of renal impairment, dose adjustments are necessary based on kidney function. For mild to moderate renal impairment (eGFR 45 to less than 90), no dose adjustment is required. However, for those with a glomerular filtration rate of 30 to less than 45, a dose of 50 mg once daily is recommended.

This medication may rarely cause serious allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after taking the medication, it should be stopped immediately, and medical attention should be sought. During the use of this medication, acute pancreatitis may occur, marked by symptoms such as abdominal pain, nausea, or vomiting; if these symptoms arise, it is crucial to visit a hospital promptly. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in patients who have had severe allergic reactions to this medication or its components. Patients with impaired kidney function may need dosage adjustments, thus regular renal function tests are advisable, and the medication should be taken according to a doctor's instructions. Cold-like symptoms or headache, dyspepsia, and diarrhea may occur during the use of this medication, and if these symptoms are severe, it is recommended to consult a doctor. Using this medication in conjunction with other hypoglycemic agents or insulin may lead to hypoglycemic symptoms; thus, frequent blood sugar monitoring is necessary, and any hypoglycemic symptoms should be addressed immediately. Severe joint pain or skin conditions such as bullous pemphigoid may occur, and immediate notification to a physician is warranted if such symptoms appear. Pregnant or breastfeeding women are advised not to use this medication, and safety and efficacy in children under 18 years have not been confirmed. Elderly patients may experience decreased renal function, thus regular monitoring of kidney function before and after taking this medication is essential. In case of overdose, standard emergency measures should be taken, and if necessary, blood dialysis can be used to remove the medication, so visit a medical institution immediately. This medication does not have major interactions with other medications, but caution is needed when taking certain medications, so always inform your doctor or pharmacist of all medications being taken.

Serious side effects

Severe hypersensitivity reactions (including urticaria, angioedema, anaphylaxis), Stevens-Johnson syndrome and exfoliative skin diseases, acute pancreatitis (hemorrhagic or necrotizing), acute renal failure, severe and disabling joint pain, bullous pemphigoid, elevated liver enzymes, liver abnormalities (risk of jaundice), severe hypoglycemia, pneumonia, diabetic complications, metabolic acidosis, falls, cardiac arrest, interstitial lung disease, rhabdomyolysis

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to protect it from air. It is recommended to store it at room temperature between 1 and 30 degrees Celsius. Storing it this way will maintain its effectiveness and ensure safe use.

Appearance

Light orange, round, double convex film-coated tablet

Package unit

30 tablets - 10 tablets/PTP[x3]