Levocetirizine Tablets (Levocetirizine Hydrochloride)

Adult dose

Adults: Take 1 tablet (5 mg of Levocetirizine Hydrochloride) orally once daily, regardless of meals. Patients with renal impairment should adjust the dose based on kidney function (creatinine clearance). - Mild (50 ≤ CLCR < 80): 1 tablet once daily - Moderate (30 ≤ CLCR < 50): 1 tablet twice daily - Severe (10 ≤ CLCR < 30): 1 tablet three times daily

Child dose

Children over 6 years: Take 1 tablet (Levocetirizine Hydrochloride 5 mg) orally once daily, regardless of meals.

This medication should not be used in patients with known allergies to any of the ingredients or who have experienced hypersensitivity reactions. It should not be administered to patients with severely impaired kidney function or those undergoing dialysis. It is also advisable for pregnant women, those who may become pregnant, and breastfeeding women to avoid taking this medication. Infants under 1 year of age should not be given this medicine, and children under 6 years should be administered in liquid form instead of tablets. Since this tablet contains lactose, it should not be used in patients with lactose intolerance or related genetic conditions. Patients with reduced kidney or liver function, as well as the elderly, should use this medication with caution, as it may remain in the body for a longer duration. Be cautious when driving or operating machinery as this medication can cause drowsiness, headache, or dizziness. Using this medication with alcohol or central nervous system depressants may increase drowsiness and impair concentration, so it is advisable not to take them together. Patients with urinary function issues or those at risk of urinary retention, such as benign prostatic hyperplasia, should exercise special caution when using this medication. As with other antihistamines, the risk of side effects may increase when combined with alcohol. It is safest for pregnant or breastfeeding women not to take this medication due to insufficient studies. Children should use appropriate dosages adjusted for age and weight, and this medication should not be used in infants under 1 year of age. Elderly patients may experience prolonged retention of the drug in the body due to reduced kidney function, so it is advisable to start at a lower dose and monitor their condition. Stopping this medication for a certain period before allergy tests can help avoid affecting test results. In case of an overdose, symptoms such as drowsiness or agitation may occur, and as there are no specific antidotes, supportive treatment should be sought. This medication is not removed by dialysis, so proper medical management is needed in cases of overdose.

Serious side effects

• Urticaria, severe swelling (angioedema)
• Chest tightness, difficulty breathing, respiratory distress, bronchospasm
• Cold sweat, pallor → Anaphylactic shock
• Severe rash with fever, blisters, peeling skin, pain in mucous membranes of the mouth and eyes → Severe skin adverse reaction
• Yellowing of the skin or eyes (jaundice), extreme lethargy → Liver abnormality
• Sudden and severe headache, lightning headache, seizures, confusion, visual disturbances

Mild side effects

• Drowsiness, lethargy, headache, numbness, fatigue, dizziness, heaviness in the head, excitement
• Dry mouth, dry lips, nausea, loss of appetite, abdominal discomfort, dyspepsia, abdominal pain, stomach discomfort, vomiting, gastrointestinal disturbances, diarrhea, cheilitis, taste disturbances
• Tachycardia, arrhythmia, increased blood pressure, palpitations
• Vasculitis, leukopenia, neutropenia, lymphocytosis, eosinophilia, monocytosis, thrombocytosis, thrombocytopenia
• Photosensitivity, rash, itching

This medication should be stored in a tightly closed container that can block light, at a temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the drug over time.

Appearance

White or pale yellow oval film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle