Olmesartan Medoxomil and Rosuvastatin Tablet 20/10 mg

Adult dose

The recommended initial dose of Olmesartan Medoxomil is 10 mg once daily, administered regardless of meals. If blood pressure is not adequately controlled, the dosage can be increased to 20 mg once daily, with a maximum dose of 40 mg per day. The antihypertensive effect typically appears within 2 weeks after initiating treatment, with maximum effectiveness occurring around 8 weeks. If blood pressure control is inadequate, adjunctive treatment with diuretics may be considered.

Child dose

Safety and efficacy in children under 18 years have not been established.

This medication can cause serious harm to the fetus and newborn if administered to pregnant women in the second and third trimesters; therefore, it should be discontinued immediately if pregnancy is confirmed. This medication should not be administered to specific patients, including those with an allergy to this medication or its components, pregnant women or women of childbearing potential, nursing mothers, patients with severely impaired renal function, those with severe liver disease, bile duct obstruction, or muscle disorders. In patients with low blood pressure or low salt levels, hypotension may occur upon the initial administration of this medication, thus careful observation is required during administration. Patients with impaired kidney function, kidney transplant recipients, those with renovascular hypertension, or patients at risk of hyperkalemia should undergo regular monitoring of kidney function and serum potassium levels when receiving this medication. This medication may affect liver function, thus patients with a history of liver disease or elevated liver enzyme levels should undergo periodic liver function tests. Muscle pain or myopathy may occur, and rarely rhabdomyolysis may occur; therefore, if symptoms such as muscle pain, weakness, or cramps arise, consultation with a physician should be sought immediately. Caution should be exercised when this medication is used by patients who consume excessive alcohol or have a history of liver disease. Dizziness may occur due to blood pressure-lowering effects; thus, caution is advised during high-altitude work or when operating dangerous machinery, including driving. This medication may interact with other drugs, especially potassium-sparing diuretics, potassium supplements, lithium, non-steroidal anti-inflammatory drugs, other antihypertensives, certain antibiotics, and antifungals; hence, inform your physician or pharmacist when taking these medications together. Women who are pregnant or breastfeeding should not use this medication, and women of childbearing potential should employ suitable contraceptive methods. Safety and efficacy in children under 18 years have not been established; therefore, avoid use in this age group. Elderly patients may have different metabolic rates and thus dosage adjustments and careful observation are necessary during administration. In the case of overdose, hypotension or heart abnormalities may occur, and immediate medical assistance should be sought; there is no specific antidote for this medication. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling of the skin, oral/ocular mucosal pain, breathlessness or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice, profound lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination issues

Mild side effects

Headache, dizziness, decreased sensation, drowsiness, gastroesophageal reflux, constipation, dental caries, dyspepsia, gastric ulcer, gastritis, gastroenteritis, musculoskeletal stiffness, atrial fibrillation, hypoglycemia, chest pain, rash, angioedema, weakness, vomiting, chronic malabsorption syndrome-like intestinal diseases, intestinal vascular edema, hyperkalemia, increased blood pressure, facial swelling, back pain, cough, nosebleed, upper respiratory tract infections, asthma, thrombocytopenia, hair loss, itching, arthralgia, arthritis, myopathy

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is recommended to keep it at a cool room temperature between 1 and 30 degrees Celsius.

Appearance

White or yellowish round film-coated tablets

Package unit

30 tablets/box [(10 tablets/Alu-Alu) × 3]